Title |
Long-term effects of intravenous iloprost in patients with idiopathic pulmonary arterial hypertension deteriorating on non-parenteral therapy
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Published in |
BMC Pulmonary Medicine, December 2011
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DOI | 10.1186/1471-2466-11-56 |
Pubmed ID | |
Authors |
Lars Knudsen, Alexander Schurawlew, Nils Nickel, Henning Tiede, Hossein A Ghofrani, Heinrike Wilkens, Ralf Ewert, Michael Halank, Hans Klose, Carlos Bäzner, Jürgen Behr, Marius M Hoeper |
Abstract |
The majority of patients with idiopathic pulmonary arterial hypertension (IPAH) in functional classes II and III are currently being treated with non-parenteral therapies, including endothelin receptor antagonists (ERA), phosphodiesterase (PDE)-5 inhibitors, inhaled iloprost or combinations of these substances. If these treatments fail, current guidelines recommend the addition of parenteral prostanoid therapy. There is, however, limited evidence for the efficacy of parenteral prostanoids when added to combinations of non-parenteral therapies. |
X Demographics
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Spain | 1 | 50% |
Unknown | 1 | 50% |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
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Germany | 1 | 3% |
Brazil | 1 | 3% |
Unknown | 27 | 93% |
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Researcher | 5 | 17% |
Student > Bachelor | 3 | 10% |
Student > Master | 3 | 10% |
Other | 4 | 14% |
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Agricultural and Biological Sciences | 1 | 3% |
Other | 0 | 0% |
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