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Effects of transcranial focused ultrasound on human primary motor cortex using 7T fMRI: a pilot study

Overview of attention for article published in BMC Neuroscience, September 2018
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  • Good Attention Score compared to outputs of the same age (67th percentile)

Mentioned by

7 tweeters


15 Dimensions

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51 Mendeley
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Effects of transcranial focused ultrasound on human primary motor cortex using 7T fMRI: a pilot study
Published in
BMC Neuroscience, September 2018
DOI 10.1186/s12868-018-0456-6
Pubmed ID

Leo Ai, Priya Bansal, Jerel K. Mueller, Wynn Legon


Transcranial focused ultrasound (tFUS) is a new non-invasive neuromodulation technique that uses mechanical energy to modulate neuronal excitability with high spatial precision. tFUS has been shown to be capable of modulating EEG brain activity in humans that is spatially restricted, and here, we use 7T MRI to extend these findings. We test the effect of tFUS on 7T BOLD fMRI signals from individual finger representations in the human primary motor cortex (M1) and connected cortical motor regions. Participants (N = 5) performed a cued finger tapping task in a 7T MRI scanner with their thumb, index, and middle fingers to produce a BOLD signal for individual M1 finger representations during either tFUS or sham neuromodulation to the thumb representation. Results demonstrated a statistically significant increase in activation volume of the M1 thumb representation for the tFUS condition as compared to sham. No differences in percent BOLD changes were found. This effect was spatially confined as the index and middle finger M1 finger representations did not show similar significant changes in either percent change or activation volume. No effects were seen during tFUS to M1 in the supplementary motor area or the dorsal premotor cortex. Single element tFUS can be paired with high field MRI that does not induce significant artifact. tFUS increases activation volumes of the targeted finger representation that is spatially restricted within M1 but does not extend to functionally connected motor regions. Trial registration ClinicalTrials.gov NCT03634631 08/14/18.

Twitter Demographics

The data shown below were collected from the profiles of 7 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 9 18%
Researcher 8 16%
Student > Ph. D. Student 7 14%
Student > Bachelor 6 12%
Professor > Associate Professor 5 10%
Other 8 16%
Unknown 8 16%
Readers by discipline Count As %
Engineering 14 27%
Medicine and Dentistry 7 14%
Psychology 4 8%
Neuroscience 3 6%
Agricultural and Biological Sciences 2 4%
Other 9 18%
Unknown 12 24%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 September 2019.
All research outputs
of 14,574,738 outputs
Outputs from BMC Neuroscience
of 1,074 outputs
Outputs of similar age
of 227,183 outputs
Outputs of similar age from BMC Neuroscience
of 3 outputs
Altmetric has tracked 14,574,738 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 1,074 research outputs from this source. They receive a mean Attention Score of 3.7. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,183 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them