Title |
Short and long-term effects of pulmonary rehabilitation in interstitial lung diseases: a randomised controlled trial
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Published in |
Respiratory Research, September 2018
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DOI | 10.1186/s12931-018-0884-y |
Pubmed ID | |
Authors |
Silvia Perez-Bogerd, Wim Wuyts, Veronica Barbier, Heleen Demeyer, Alain Van Muylem, Wim Janssens, Thierry Troosters |
Abstract |
Few data are available on the long-term effect of pulmonary rehabilitation (PR) and on long PR programs in interstitial lung diseases (ILD). We aimed to evaluate the effects of PR on exercise capacity (6-Minute Walking Distance, 6MWD; Peak Work Rate, Wmax), quality of life (St George's Respiratory Questionnaire, SGRQ), quadriceps force (QF) and objectively measured physical activity in ILD after the 6-month PR-program and after 1 year. 60 patients (64 ± 11 years; 62% males; 23% with IPF) were randomly assigned to receive a 6 month-PR program or usual medical care. Exercise capacity, quality of life and muscle force increased significantly after the program as compared to control (mean,95%CI[ll to ul]; 6MWD + 72,[36 to 108] m; Wmax 19, [8 to 29]%pred; SGRQ - 12,[- 19 to - 6] points; QF 10, [1 to 18] %pred). The gain was sustained after 1 year (6MWD 73,[28 to 118] m; Wmax 23, [10 to 35]%pred; SGRQ - 11,[- 18 to - 4] points; QF 9.5, [1 to 18] %pred). Physical activity did not change. PR improves exercise tolerance, health status and muscle force in ILD. The benefits are maintained at 1-year follow-up. The intervention did not change physical activity. Clinicaltrials.gov NCT00882817 . |
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Moldova, Republic of | 1 | 1% |
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Demographic breakdown
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Scientists | 16 | 17% |
Practitioners (doctors, other healthcare professionals) | 14 | 15% |
Science communicators (journalists, bloggers, editors) | 2 | 2% |
Mendeley readers
Geographical breakdown
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Unknown | 154 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 25 | 16% |
Student > Master | 14 | 9% |
Other | 12 | 8% |
Student > Ph. D. Student | 9 | 6% |
Researcher | 8 | 5% |
Other | 21 | 14% |
Unknown | 65 | 42% |
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Sports and Recreations | 8 | 5% |
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Neuroscience | 2 | 1% |
Other | 4 | 3% |
Unknown | 71 | 46% |