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Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors

Overview of attention for article published in Investigational New Drugs, October 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#22 of 1,168)
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (80th percentile)

Mentioned by

blogs
2 blogs
patent
30 patents

Citations

dimensions_citation
71 Dimensions

Readers on

mendeley
52 Mendeley
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Title
Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors
Published in
Investigational New Drugs, October 2006
DOI 10.1007/s10637-006-9017-4
Pubmed ID
Authors

Luis H. Camacho, Jon Olson, William P. Tong, Charles W. Young, David R. Spriggs, Mark G. Malkin

Abstract

Phenylbutyrate (PBA), and its metabolite phenylacetate (PAA), induce growth inhibition and cellular differentiation in multiple tumor models. However, despite their potential anti-cancer properties, several pharmacodynamic aspects remain unknown.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 9 17%
Student > Bachelor 8 15%
Student > Ph. D. Student 8 15%
Professor > Associate Professor 4 8%
Lecturer 2 4%
Other 5 10%
Unknown 16 31%
Readers by discipline Count As %
Medicine and Dentistry 14 27%
Agricultural and Biological Sciences 6 12%
Biochemistry, Genetics and Molecular Biology 4 8%
Psychology 4 8%
Nursing and Health Professions 3 6%
Other 4 8%
Unknown 17 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 24. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2024.
All research outputs
#1,321,330
of 22,757,090 outputs
Outputs from Investigational New Drugs
#22
of 1,168 outputs
Outputs of similar age
#2,271
of 67,087 outputs
Outputs of similar age from Investigational New Drugs
#1
of 5 outputs
Altmetric has tracked 22,757,090 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 94th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,168 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 67,087 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them