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Evaluation of the Cutaneous Lymphoma International Prognostic Index in patients with early stage mycosis fungoides

Overview of attention for article published in Anais Brasileiros de Dermatologia, October 2018
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Title
Evaluation of the Cutaneous Lymphoma International Prognostic Index in patients with early stage mycosis fungoides
Published in
Anais Brasileiros de Dermatologia, October 2018
DOI 10.1590/abd1806-4841.20187134
Pubmed ID
Authors

Gustavo Moreira Amorim, João Paulo Niemeyer Corbellini, Danielle Carvalho Quintella, Tullia Cuzzi, Márcia Ramos-e-Silva

Abstract

Mycosis fungoides (MF) is the most common subtype of cutaneous T-cell lymphoma. TNMB system is the staging method used in MF, and it not only guides therapeutic management, but represents the main prognostic factor. In order to improve the prognostic evaluation, the Cutaneous Lymphoma International Prognostic Index (CLIPi) was proposed. To evaluate the performance of CLIPi score for prognostic analysis in patients with early stage MF. This is a retrospective cross-sectional observational study, with exploratory analysis. The outcome variables were disease progression and related death. One hundred and two patients were stratified according to CLIPi score, being the majority classified as low risk. Patients with intermediate or high risk presented disease progression more frequently than those with low risk (PR: 1.2 / p = 0.004 / 95%CI: 1.0 - 1.6). The same did not occur with the variable related death. In addition, survival rates were not consistent with risk stratification. Small sample and its retrospective analysis. Since CLIPi score was proposed, four other studies that we could consult showed conflicting results, similar to the present study. Further studies are necessary for a recommendation of its use.

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Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 3 17%
Student > Postgraduate 2 11%
Student > Bachelor 1 6%
Researcher 1 6%
Student > Doctoral Student 1 6%
Other 0 0%
Unknown 10 56%
Readers by discipline Count As %
Medicine and Dentistry 4 22%
Agricultural and Biological Sciences 2 11%
Nursing and Health Professions 1 6%
Pharmacology, Toxicology and Pharmaceutical Science 1 6%
Unknown 10 56%