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Mendeley readers
Attention Score in Context
| Title |
Advanced Glycation End-Products as Markers of Aging and Longevity in the Long-Lived Ansell’s Mole-Rat (Fukomys anselli)
|
|---|---|
| Published in |
Journals of Gerontology Series A: Biological Sciences & Medical Sciences, December 2011
|
| DOI | 10.1093/gerona/glr208 |
| Pubmed ID | |
| Authors |
Philip Dammann, David R. Sell, Sabine Begall, Christopher Strauch, Vincent M. Monnier |
| Abstract |
Mole-rat of the genus Fukomys are mammals whose life span is strongly influenced by reproductive status with breeders far outliving nonbreeders. This raises the important question of whether increased longevity of the breeders is reflected in atypical expression of biochemical markers of aging. Here, we measured markers of glycation and advanced glycation end-products formed in insoluble skin collagen of Ansell's mole-rat Fukomys anselli as a function of age and breeding status. Glucosepane, pentosidine, and total advanced glycation end-product content significantly increased with age after correction for breeder status and sex. Unexpectedly, total advanced glycation end-products, glucosepane, and carboxymethyl-lysine (CML) were significantly higher in breeders versus nonbreeders suggesting that breeders have evolved powerful defenses against combined oxidant and carbonyl stress compared with nonbreeders. Most interestingly, when compared with other mammals, pentosidine formation rate was lower in mole-rat compared with other short-lived rodents confirming previous observations of an inverse relationship between longevity and pentosidine formation rates in skin collagen. |
Mendeley readers
The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 57 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 21% |
| Student > Master | 9 | 16% |
| Student > Bachelor | 8 | 14% |
| Student > Ph. D. Student | 5 | 9% |
| Student > Postgraduate | 3 | 5% |
| Other | 5 | 9% |
| Unknown | 15 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 19 | 33% |
| Biochemistry, Genetics and Molecular Biology | 6 | 11% |
| Medicine and Dentistry | 4 | 7% |
| Business, Management and Accounting | 2 | 4% |
| Environmental Science | 2 | 4% |
| Other | 8 | 14% |
| Unknown | 16 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2011.
All research outputs
#4,217,336
of 25,655,374 outputs
Outputs from Journals of Gerontology Series A: Biological Sciences & Medical Sciences
#1,325
of 3,998 outputs
Outputs of similar age
#32,133
of 247,900 outputs
Outputs of similar age from Journals of Gerontology Series A: Biological Sciences & Medical Sciences
#5
of 18 outputs
Altmetric has tracked 25,655,374 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,998 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.3. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,900 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.