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Crystalloid podocytopathy with focal segmental glomerulosclerosis in PCM: a case report

Overview of attention for article published in Diagnostic Pathology, December 2015
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Title
Crystalloid podocytopathy with focal segmental glomerulosclerosis in PCM: a case report
Published in
Diagnostic Pathology, December 2015
DOI 10.1186/s13000-015-0448-0
Pubmed ID
Authors

You La Jeon, Woo In Lee, Yujin Choi, So Young Kang, Myeong Hee Kim, Sung-Jig Lim, Sang Ho Lee

Abstract

Crystalloid podocytopathy with focal segmental glomerulosclerosis in plasma cell myeloma (PCM) is rare. We present a case of crystalline deposition in the bone marrow (BM) and various renal cells with only proteinuria as a symptom. As workup for proteinuria, a renal biopsy sample was obtained. EM showed multiple crystalline depositions in renal tubular cells and podocytes. Focal segmental glomerulosclerosis with crystalloid podocytopathy was diagnosed. Because monoclonal gammopathy was detected in the serum and urine, a BM study was also performed. Plasma cells with needle-shaped inclusion bodies were observed. The crystalline deposits in the plasma cells and podocytes were positive for Masson's trichrome and kappa light-chain staining. These findings indicated that the crystalline deposits originated from paraprotein. The case showed a rare process of focal segmental glomerulosclerosis via crystalline deposition in podocytes in plasma cell myeloma. Crystalloid podocytopathy is a likely cause of renal damage such as FSGS in PCM, although it is an uncommon mechanism for myeloma kidney.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Thailand 1 6%
Unknown 16 94%

Demographic breakdown

Readers by professional status Count As %
Other 4 24%
Researcher 3 18%
Student > Bachelor 2 12%
Lecturer > Senior Lecturer 1 6%
Student > Master 1 6%
Other 3 18%
Unknown 3 18%
Readers by discipline Count As %
Medicine and Dentistry 13 76%
Biochemistry, Genetics and Molecular Biology 1 6%
Unknown 3 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 June 2018.
All research outputs
#14,243,953
of 22,837,982 outputs
Outputs from Diagnostic Pathology
#422
of 1,128 outputs
Outputs of similar age
#204,222
of 390,455 outputs
Outputs of similar age from Diagnostic Pathology
#14
of 43 outputs
Altmetric has tracked 22,837,982 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,128 research outputs from this source. They receive a mean Attention Score of 2.8. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 390,455 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.