@CeciliaNordens1 https://t.co/itulRMga7v Please note that ZIP proteins harboring CFC sequences N-terminal to their transmembrane domains can be found in organisms with relatively primitive body plans such as hydra (H. magnipapillata)
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"Modern-day prion proteins as remnants of an ancient involvement in the sensing and/or import of metal ions." https://t.co/uT3PPz1eD2
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"This finding provides a rationale for structural and biological features within modern-day prion proteins." https://t.co/uT3PPz1eD2
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"The prion gene family is phylogenetically derived from a ZIP-like ancestral molecule." https://t.co/uT3PPz1eD2