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Full thickness macular hole case after intravitreal aflibercept treatment

Overview of attention for article published in BMC Ophthalmology, March 2015
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Title
Full thickness macular hole case after intravitreal aflibercept treatment
Published in
BMC Ophthalmology, March 2015
DOI 10.1186/s12886-015-0021-3
Pubmed ID
Authors

Yuji Oshima, Rajendra S Apte, Shintaro Nakao, Shigeo Yoshida, Tatsuro Ishibashi

Abstract

The pathogenesis of macular hole formation is widely accepted as a tractional force at the vitreo-retinal interface in fovea. We report a case of macular hole after intravitreous aflibercept injection for age-related macular degeneration (AMD) associated with contraction of the retinal pigment epithelium (RPE) at the edge of a fibrovascular pigment epithelial detachment (PED). A 94-year old man with neovascular AMD affecting his left eye accompanied by a fibrovascular PED was examined for severe vision loss. Although RPE tear in his left eye was identified before the first aflibercept intravitreous injection performed in order to treat neovascular AMD, he received three aflibercept injections as induction treatment. After induction treatment, a full thickness macular hole was identified associated with the contracted rolled RPE edge beneath the retina. Macular hole is commonly formed associated with tangential vitreous traction. Current report suggests that rapid contraction of the RPE underneath the retina can be one of the causes of a macular hole, and one of the side effects of anti-VEGF therapy for neovascular AMD.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 31 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 23%
Student > Bachelor 4 13%
Student > Ph. D. Student 4 13%
Student > Postgraduate 3 10%
Professor > Associate Professor 3 10%
Other 5 16%
Unknown 5 16%
Readers by discipline Count As %
Medicine and Dentistry 18 58%
Arts and Humanities 1 3%
Biochemistry, Genetics and Molecular Biology 1 3%
Chemical Engineering 1 3%
Agricultural and Biological Sciences 1 3%
Other 1 3%
Unknown 8 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2016.
All research outputs
#20,302,535
of 22,840,638 outputs
Outputs from BMC Ophthalmology
#2,084
of 2,347 outputs
Outputs of similar age
#223,583
of 264,076 outputs
Outputs of similar age from BMC Ophthalmology
#21
of 28 outputs
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So far Altmetric has tracked 2,347 research outputs from this source. They receive a mean Attention Score of 2.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.