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Full thickness macular hole case after intravitreal aflibercept treatment

Overview of attention for article published in BMC Ophthalmology, March 2015
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Title
Full thickness macular hole case after intravitreal aflibercept treatment
Published in
BMC Ophthalmology, March 2015
DOI 10.1186/s12886-015-0021-3
Pubmed ID
Authors

Yuji Oshima, Rajendra S Apte, Shintaro Nakao, Shigeo Yoshida, Tatsuro Ishibashi

Abstract

The pathogenesis of macular hole formation is widely accepted as a tractional force at the vitreo-retinal interface in fovea. We report a case of macular hole after intravitreous aflibercept injection for age-related macular degeneration (AMD) associated with contraction of the retinal pigment epithelium (RPE) at the edge of a fibrovascular pigment epithelial detachment (PED). A 94-year old man with neovascular AMD affecting his left eye accompanied by a fibrovascular PED was examined for severe vision loss. Although RPE tear in his left eye was identified before the first aflibercept intravitreous injection performed in order to treat neovascular AMD, he received three aflibercept injections as induction treatment. After induction treatment, a full thickness macular hole was identified associated with the contracted rolled RPE edge beneath the retina. Macular hole is commonly formed associated with tangential vitreous traction. Current report suggests that rapid contraction of the RPE underneath the retina can be one of the causes of a macular hole, and one of the side effects of anti-VEGF therapy for neovascular AMD.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 5 29%
Student > Ph. D. Student 4 24%
Student > Postgraduate 3 18%
Student > Bachelor 2 12%
Other 1 6%
Other 2 12%
Readers by discipline Count As %
Medicine and Dentistry 11 65%
Unspecified 4 24%
Social Sciences 1 6%
Arts and Humanities 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 January 2016.
All research outputs
#6,012,593
of 7,003,089 outputs
Outputs from BMC Ophthalmology
#333
of 479 outputs
Outputs of similar age
#259,301
of 316,071 outputs
Outputs of similar age from BMC Ophthalmology
#15
of 24 outputs
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