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Age-Related Neural Dedifferentiation in the Motor System

Overview of attention for article published in PLOS ONE, December 2011
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Title
Age-Related Neural Dedifferentiation in the Motor System
Published in
PLOS ONE, December 2011
DOI 10.1371/journal.pone.0029411
Pubmed ID
Authors

Joshua Carp, Joonkoo Park, Andrew Hebrank, Denise C. Park, Thad A. Polk

Abstract

Recent neuroimaging studies using multi-voxel pattern analysis (MVPA) show that distributed patterns of brain activation elicited by different visual stimuli are less distinctive in older adults than in young adults. However, less is known about the effects of aging on the neural representation of movement. The present study used MVPA to compare the distinctiveness of motor representations in young and older adults. We also investigated the contributions of brain structure to age differences in the distinctiveness of motor representations. We found that neural distinctiveness was reduced in older adults throughout the motor control network. Although aging was also associated with decreased gray matter volume in these regions, age differences in motor distinctiveness remained significant after controlling for gray matter volume. Our results suggest that age-related neural dedifferentiation is not restricted to sensory perception and is instead a more general feature of the aging brain.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 145 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 2 1%
Germany 2 1%
Canada 2 1%
Hungary 1 <1%
Australia 1 <1%
Austria 1 <1%
Sweden 1 <1%
Belgium 1 <1%
Unknown 134 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 25%
Researcher 19 13%
Student > Master 15 10%
Student > Bachelor 12 8%
Student > Doctoral Student 7 5%
Other 24 17%
Unknown 32 22%
Readers by discipline Count As %
Psychology 39 27%
Neuroscience 26 18%
Medicine and Dentistry 14 10%
Agricultural and Biological Sciences 10 7%
Nursing and Health Professions 4 3%
Other 11 8%
Unknown 41 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 December 2011.
All research outputs
#18,303,139
of 22,660,862 outputs
Outputs from PLOS ONE
#153,700
of 193,497 outputs
Outputs of similar age
#195,524
of 243,133 outputs
Outputs of similar age from PLOS ONE
#2,187
of 2,927 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,497 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
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We're also able to compare this research output to 2,927 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.