Title |
The bending of cell sheets - from folding to rolling
|
---|---|
Published in |
BMC Biology, December 2011
|
DOI | 10.1186/1741-7007-9-90 |
Pubmed ID | |
Authors |
Ray Keller, David Shook |
Abstract |
The bending of cell sheets plays a major role in multicellular embryonic morphogenesis. Recent advances are leading to a deeper understanding of how the biophysical properties and the force-producing behaviors of cells are regulated, and how these forces are integrated across cell sheets during bending. We review work that shows that the dynamic balance of apical versus basolateral cortical tension controls specific aspects of invagination of epithelial sheets, and recent evidence that tissue expansion by growth contributes to neural retinal invagination in a stem cell-derived, self-organizing system. Of special interest is the detailed analysis of the type B inversion in Volvox reported in BMC Biology by Höhn and Hallmann, as this is a system that promises to be particularly instructive in understanding morphogenesis of any monolayered spheroid system. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 1 | 25% |
United Kingdom | 1 | 25% |
Unknown | 2 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 75% |
Scientists | 1 | 25% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 2% |
Australia | 1 | 2% |
United Kingdom | 1 | 2% |
Iran, Islamic Republic of | 1 | 2% |
Spain | 1 | 2% |
United States | 1 | 2% |
Unknown | 58 | 91% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 34% |
Researcher | 17 | 27% |
Professor | 4 | 6% |
Student > Bachelor | 4 | 6% |
Professor > Associate Professor | 3 | 5% |
Other | 8 | 13% |
Unknown | 6 | 9% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 35 | 55% |
Biochemistry, Genetics and Molecular Biology | 14 | 22% |
Physics and Astronomy | 4 | 6% |
Chemistry | 2 | 3% |
Computer Science | 1 | 2% |
Other | 2 | 3% |
Unknown | 6 | 9% |