↓ Skip to main content

Decreased miR-198 expression and its prognostic significance in human gastric cancer

Overview of attention for article published in World Journal of Surgical Oncology, February 2016
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
1 tweeter

Citations

dimensions_citation
16 Dimensions

Readers on

mendeley
13 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Decreased miR-198 expression and its prognostic significance in human gastric cancer
Published in
World Journal of Surgical Oncology, February 2016
DOI 10.1186/s12957-016-0784-x
Pubmed ID
Authors

Zhigang Cui, Xin Zheng, Di Kong

Abstract

MicroRNAs (miRNAs) have been proved to play important roles in the tumorigenesis and development of human gastric cancer (GC). Our study aims to investigate the expression and clinical significance of miR-198 in GC patients. Quantitative real-time polymerase chain reaction (RT-PCR) was performed to evaluate miR-198 levels in 106 pairs of GC specimens and adjacent noncancerous tissues. Then, the associations of miR-198 expression with clinicopathological factors and patient's survival were determined. The expression levels of miR-198 in GC tissues were significantly lower than those in corresponding noncancerous tissues (p < 0.01). Decreased miR-198 expression was significantly associated with larger tumor size, deeper invasion depth, positive lymph node metastasis, advanced tumor-node-metastasis (TNM) stage, and shorter overall survival. Moreover, multivariate regression analysis identified low miR-198 expression as an independent predictor of poor survival. These findings suggested that miR-198 downregulation may be associated with progression of GC and that this miR may be an independent prognostic marker for GC patients.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 5 38%
Researcher 3 23%
Student > Ph. D. Student 2 15%
Student > Master 2 15%
Unspecified 1 8%
Other 0 0%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 6 46%
Medicine and Dentistry 3 23%
Agricultural and Biological Sciences 2 15%
Neuroscience 1 8%
Unspecified 1 8%
Other 0 0%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 February 2016.
All research outputs
#5,363,862
of 7,140,824 outputs
Outputs from World Journal of Surgical Oncology
#576
of 1,182 outputs
Outputs of similar age
#221,984
of 320,601 outputs
Outputs of similar age from World Journal of Surgical Oncology
#14
of 38 outputs
Altmetric has tracked 7,140,824 research outputs across all sources so far. This one is in the 13th percentile – i.e., 13% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,182 research outputs from this source. They receive a mean Attention Score of 1.3. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,601 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 17th percentile – i.e., 17% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one is in the 47th percentile – i.e., 47% of its contemporaries scored the same or lower than it.