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Mendeley readers
Attention Score in Context
| Title |
Age influences DNA methylation and gene expression of COX7A1 in human skeletal muscle
|
|---|---|
| Published in |
Diabetologia, May 2008
|
| DOI | 10.1007/s00125-008-1018-8 |
| Pubmed ID | |
| Authors |
T. Rönn, P. Poulsen, O. Hansson, J. Holmkvist, P. Almgren, P. Nilsson, T. Tuomi, B. Isomaa, L. Groop, A. Vaag, C. Ling |
| Abstract |
Reduced oxidative capacity of the mitochondria in skeletal muscle has been suggested to contribute to insulin resistance and type 2 diabetes. Moreover, a set of genes influencing oxidative phosphorylation (OXPHOS) is downregulated in diabetic muscle. Here we studied whether genetic, epigenetic and non-genetic factors influence a component of the respiratory chain, COX7A1, previously shown to be downregulated in skeletal muscle from patients with type 2 diabetes. The specific aims were to: (1) evaluate the impact of genetic (single nucleotide polymorphisms [SNPs]), epigenetic (DNA methylation) and non-genetic (age) factors on the expression of COX7A1 in human skeletal muscle; and (2) investigate whether common variants in the COX7A1 gene are associated with increased risk of type 2 diabetes. |
Mendeley readers
The data shown below were compiled from readership statistics for 124 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 2 | 2% |
| Korea, Republic of | 1 | <1% |
| United Kingdom | 1 | <1% |
| India | 1 | <1% |
| Canada | 1 | <1% |
| Japan | 1 | <1% |
| Unknown | 117 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 25 | 20% |
| Researcher | 23 | 19% |
| Professor > Associate Professor | 15 | 12% |
| Student > Master | 15 | 12% |
| Student > Doctoral Student | 7 | 6% |
| Other | 22 | 18% |
| Unknown | 17 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 36 | 29% |
| Biochemistry, Genetics and Molecular Biology | 30 | 24% |
| Medicine and Dentistry | 23 | 19% |
| Sports and Recreations | 4 | 3% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 2% |
| Other | 10 | 8% |
| Unknown | 19 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 April 2023.
All research outputs
#3,945,616
of 23,572,509 outputs
Outputs from Diabetologia
#1,791
of 5,134 outputs
Outputs of similar age
#13,399
of 84,638 outputs
Outputs of similar age from Diabetologia
#8
of 31 outputs
Altmetric has tracked 23,572,509 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,134 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 23.4. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 84,638 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.