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Antimalarial Drug Quality in the Most Severely Malarious Parts of Africa – A Six Country Study

Overview of attention for article published in PLOS ONE, May 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (96th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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mendeley
159 Mendeley
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1 Connotea
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Title
Antimalarial Drug Quality in the Most Severely Malarious Parts of Africa – A Six Country Study
Published in
PLOS ONE, May 2008
DOI 10.1371/journal.pone.0002132
Pubmed ID
Authors

Roger Bate, Philip Coticelli, Richard Tren, Amir Attaran

Abstract

A range of antimalarial drugs were procured from private pharmacies in urban and peri-urban areas in the major cities of six African countries, situated in the part of that continent and the world that is most highly endemic for malaria. Semi-quantitative thin-layer chromatography (TLC) and dissolution testing were used to measure active pharmaceutical ingredient content against internationally acceptable standards. 35% of all samples tested failed either or both tests, and were substandard. Further, 33% of treatments collected were artemisinin monotherapies, most of which (78%) were manufactured in disobservance of an appeal by the World Health Organisation (WHO) to withdraw these clinically inappropriate medicines from the market. The high persistence of substandard drugs and clinically inappropriate artemisinin monotherapies in the private sector risks patient safety and, through drug resistance, places the future of malaria treatment at risk globally.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 159 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 5 3%
Belgium 1 <1%
Unknown 153 96%

Demographic breakdown

Readers by professional status Count As %
Student > Master 34 21%
Student > Ph. D. Student 21 13%
Researcher 16 10%
Student > Bachelor 16 10%
Other 9 6%
Other 35 22%
Unknown 28 18%
Readers by discipline Count As %
Medicine and Dentistry 43 27%
Agricultural and Biological Sciences 24 15%
Pharmacology, Toxicology and Pharmaceutical Science 13 8%
Social Sciences 11 7%
Chemistry 6 4%
Other 33 21%
Unknown 29 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 23. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2013.
All research outputs
#1,363,947
of 22,660,862 outputs
Outputs from PLOS ONE
#17,951
of 193,497 outputs
Outputs of similar age
#3,048
of 78,676 outputs
Outputs of similar age from PLOS ONE
#39
of 336 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,497 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 78,676 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 96% of its contemporaries.
We're also able to compare this research output to 336 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.