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Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels

Overview of attention for article published in Genome Biology, June 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

Mentioned by

blogs
1 blog
f1000
1 research highlight platform

Citations

dimensions_citation
72 Dimensions

Readers on

mendeley
152 Mendeley
citeulike
7 CiteULike
connotea
2 Connotea
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Title
Active DNA demethylation in human postmitotic cells correlates with activating histone modifications, but not transcription levels
Published in
Genome Biology, June 2010
DOI 10.1186/gb-2010-11-6-r63
Pubmed ID
Authors

Maja Klug, Sven Heinz, Claudia Gebhard, Lucia Schwarzfischer, Stefan W Krause, Reinhard Andreesen, Michael Rehli

Abstract

In mammals, the dynamics of DNA methylation, in particular the regulated, active removal of cytosine methylation, has remained a mystery, partly due to the lack of appropriate model systems to study DNA demethylation. Previous work has largely focused on proliferating cell types that are mitotically arrested using pharmacological inhibitors to distinguish between active and passive mechanisms of DNA demethylation.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 152 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 4%
Brazil 2 1%
Germany 1 <1%
Australia 1 <1%
United Kingdom 1 <1%
Austria 1 <1%
New Zealand 1 <1%
Canada 1 <1%
Japan 1 <1%
Other 1 <1%
Unknown 136 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 43 28%
Student > Ph. D. Student 39 26%
Professor 12 8%
Student > Bachelor 11 7%
Professor > Associate Professor 11 7%
Other 21 14%
Unknown 15 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 84 55%
Biochemistry, Genetics and Molecular Biology 21 14%
Medicine and Dentistry 17 11%
Computer Science 4 3%
Mathematics 2 1%
Other 9 6%
Unknown 15 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 July 2010.
All research outputs
#4,820,810
of 25,373,627 outputs
Outputs from Genome Biology
#2,794
of 4,467 outputs
Outputs of similar age
#19,549
of 103,986 outputs
Outputs of similar age from Genome Biology
#16
of 35 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.6. This one is in the 37th percentile – i.e., 37% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 103,986 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.