↓ Skip to main content

The Structural Integrity of an Amygdala–Prefrontal Pathway Predicts Trait Anxiety

Overview of attention for article published in Journal of Neuroscience, September 2009
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (67th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (52nd percentile)

Citations

dimensions_citation
384 Dimensions

Readers on

mendeley
581 Mendeley
citeulike
3 CiteULike
connotea
1 Connotea
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
The Structural Integrity of an Amygdala–Prefrontal Pathway Predicts Trait Anxiety
Published in
Journal of Neuroscience, September 2009
DOI 10.1523/jneurosci.2335-09.2009
Pubmed ID
Authors

M Justin Kim, Paul J Whalen

Abstract

Here, we used diffusion tensor imaging (DTI) and showed that the strength of an axonal pathway identified between the amygdala and prefrontal cortex predicted individual differences in trait anxiety. A functional magnetic resonance imaging (fMRI) functional localizer that has been shown to produce reliable amygdala activation was collected in 20 psychiatrically healthy subjects. Voxelwise regression analyses using this fMRI amygdala reactivity as a regressor were performed on fractional anisotropy images derived from DTI. This analysis identified a white matter pathway between the amygdala and ventromedial prefrontal cortex. Individual differences in the structural integrity of this putative amygdala-prefrontal pathway were inversely correlated with trait anxiety levels (i.e., higher pathway strength predicted lower anxiety). More generally, this study illustrates a strategy for combining fMRI and DTI to identify individual differences in structural pathways that predict behavioral outcomes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 581 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 16 3%
Germany 5 <1%
Switzerland 3 <1%
United Kingdom 3 <1%
Australia 2 <1%
France 1 <1%
Hong Kong 1 <1%
Netherlands 1 <1%
Argentina 1 <1%
Other 5 <1%
Unknown 543 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 139 24%
Researcher 110 19%
Student > Master 70 12%
Student > Bachelor 52 9%
Student > Doctoral Student 44 8%
Other 117 20%
Unknown 49 8%
Readers by discipline Count As %
Psychology 224 39%
Neuroscience 91 16%
Medicine and Dentistry 70 12%
Agricultural and Biological Sciences 63 11%
Engineering 12 2%
Other 38 7%
Unknown 83 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 January 2012.
All research outputs
#6,377,613
of 22,660,862 outputs
Outputs from Journal of Neuroscience
#10,083
of 23,123 outputs
Outputs of similar age
#24,771
of 80,920 outputs
Outputs of similar age from Journal of Neuroscience
#88
of 218 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 23,123 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 80,920 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.
We're also able to compare this research output to 218 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.