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High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition

Overview of attention for article published in PLOS ONE, November 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (74th percentile)

Mentioned by

blogs
1 blog
patent
1 patent
f1000
1 research highlight platform

Citations

dimensions_citation
134 Dimensions

Readers on

mendeley
97 Mendeley
connotea
1 Connotea
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Title
High ALDH Activity Identifies Chemotherapy-Resistant Ewing's Sarcoma Stem Cells That Retain Sensitivity to EWS-FLI1 Inhibition
Published in
PLOS ONE, November 2010
DOI 10.1371/journal.pone.0013943
Pubmed ID
Authors

Ola Awad, Jason T. Yustein, Preeti Shah, Naheed Gul, Varalakshmi Katuri, Alison O'Neill, Yali Kong, Milton L. Brown, Jeffrey A. Toretsky, David M. Loeb

Abstract

Cancer stem cells are a chemotherapy-resistant population capable of self-renewal and of regenerating the bulk tumor, thereby causing relapse and patient death. Ewing's sarcoma, the second most common form of bone tumor in adolescents and young adults, follows a clinical pattern consistent with the Cancer Stem Cell model - remission is easily achieved, even for patients with metastatic disease, but relapse remains frequent and is usually fatal.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Switzerland 3 3%
United States 2 2%
Portugal 1 1%
Italy 1 1%
Netherlands 1 1%
United Kingdom 1 1%
Luxembourg 1 1%
Unknown 87 90%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 30%
Researcher 16 16%
Student > Bachelor 10 10%
Student > Master 9 9%
Student > Doctoral Student 6 6%
Other 15 15%
Unknown 12 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 30%
Medicine and Dentistry 21 22%
Biochemistry, Genetics and Molecular Biology 16 16%
Chemistry 4 4%
Engineering 3 3%
Other 8 8%
Unknown 16 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 January 2019.
All research outputs
#3,138,125
of 22,660,862 outputs
Outputs from PLOS ONE
#41,290
of 193,497 outputs
Outputs of similar age
#13,512
of 100,838 outputs
Outputs of similar age from PLOS ONE
#257
of 991 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 193,497 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 100,838 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 991 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.