You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
Mendeley readers
Attention Score in Context
| Title |
Genes Confer Similar Robustness to Environmental, Stochastic, and Genetic Perturbations in Yeast
|
|---|---|
| Published in |
PLOS ONE, February 2010
|
| DOI | 10.1371/journal.pone.0009035 |
| Pubmed ID | |
| Authors |
Ben Lehner |
| Abstract |
Gene inactivation often has little or no apparent consequence for the phenotype of an organism. This property-enetic (or mutational) robustness-is pervasive, and has important implications for disease and evolution, but is not well understood. Dating back to at least Waddington, it has been suggested that mutational robustness may be related to the requirement to withstand environmental or stochastic perturbations. Here I show that global quantitative data from yeast are largely consistent with this idea. Considering the effects of mutations in all nonessential genes shows that genes that confer robustness to environmental or stochastic change also buffer the effects of genetic change, and with similar efficacy. This means that selection during evolution for environmental or stochastic robustness (also referred to as canalization) may frequently have the side effect of increasing genetic robustness. A dynamic environment may therefore promote the evolution of phenotypic complexity. It also means that "hub" genes in genetic interaction (synthetic lethal) networks are generally genes that confer environmental resilience and phenotypic stability. |
Mendeley readers
The data shown below were compiled from readership statistics for 158 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 6% |
| Spain | 3 | 2% |
| United Kingdom | 3 | 2% |
| Mexico | 2 | 1% |
| Italy | 1 | <1% |
| Switzerland | 1 | <1% |
| Saudi Arabia | 1 | <1% |
| Portugal | 1 | <1% |
| Canada | 1 | <1% |
| Other | 1 | <1% |
| Unknown | 135 | 85% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 51 | 32% |
| Researcher | 38 | 24% |
| Professor > Associate Professor | 15 | 9% |
| Student > Bachelor | 14 | 9% |
| Student > Master | 11 | 7% |
| Other | 21 | 13% |
| Unknown | 8 | 5% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 106 | 67% |
| Biochemistry, Genetics and Molecular Biology | 22 | 14% |
| Computer Science | 7 | 4% |
| Medicine and Dentistry | 4 | 3% |
| Economics, Econometrics and Finance | 2 | 1% |
| Other | 7 | 4% |
| Unknown | 10 | 6% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2019.
All research outputs
#6,377,613
of 22,660,862 outputs
Outputs from PLOS ONE
#76,349
of 193,497 outputs
Outputs of similar age
#41,361
of 164,946 outputs
Outputs of similar age from PLOS ONE
#304
of 631 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 193,497 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 164,946 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 631 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.