1,438 followers
1,438 followers
@j_n_justice "it has been suggested that the mechanism of action of metformin involved the inhibition of Complex I...in vivo and in intact cells, metformin triggers a signaling pathway that in turn induces the inhibition of Complex I" https://t.co/UKeovvZy
1,379 followers
@bruno_crocco @Outdoctrination @ChrisMasterjohn @fire_bottle @TuckerGoodrich Or it may not. The whole paper is based on the premise that metformin accumulates in mitochondria (within 6h!) but produces no evidence that this is the case. It doesn't. Also, if
678 followers
RT @de_bose: @yeeseak @philosophising4 @Peace80645024 @MedEckardt @KiesowPaul @AlgoTradeAll @yeesak @daveasprey Yes. Personally, I don’t…