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Statistical Monitoring of Clinical Trials

Overview of attention for book
Cover of 'Statistical Monitoring of Clinical Trials'

Table of Contents

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    Book Overview
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    Chapter 1 Introduction
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    Chapter 2 A General Framework
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    Chapter 3 Power: Conditional, Unconditional, and Predictive
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    Chapter 4 Historical Monitoring Boundaries
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    Chapter 5 Spending Functions
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    Chapter 6 Practical Survival Monitoring
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    Chapter 7 Inference Following a Group-Sequential Trial
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    Chapter 8 Options When Brownian Motion Does Not Hold
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    Chapter 9 Monitoring for Safety
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    Chapter 10 Bayesian Monitoring
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    Chapter 11 Adaptive Sample Size Methods
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    Chapter 12 Topics Not Covered
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    Chapter 13 Appendix I: The Logrank and Related Tests
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    Chapter 14 Appendix II: Group-Sequential Software
Attention for Chapter 5: Spending Functions
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