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Mendeley readers
Attention Score in Context
| Title |
Abnormalities in Oxygen Sensing Define Early and Late Onset Preeclampsia as Distinct Pathologies
|
|---|---|
| Published in |
PLOS ONE, October 2010
|
| DOI | 10.1371/journal.pone.0013288 |
| Pubmed ID | |
| Authors |
Alessandro Rolfo, Ariel Many, Antonella Racano, Reshef Tal, Andrea Tagliaferro, Francesca Ietta, Jinxia Wang, Martin Post, Isabella Caniggia |
| Abstract |
The pathogenesis of preeclampsia, a serious pregnancy disorder, is still elusive and its treatment empirical. Hypoxia Inducible Factor-1 (HIF-1) is crucial for placental development and early detection of aberrant regulatory mechanisms of HIF-1 could impact on the diagnosis and management of preeclampsia. HIF-1α stability is controlled by O(2)-sensing enzymes including prolyl hydroxylases (PHDs), Factor Inhibiting HIF (FIH), and E3 ligases Seven In Absentia Homologues (SIAHs). Here we investigated early- (E-PE) and late-onset (L-PE) human preeclamptic placentae and their ability to sense changes in oxygen tension occurring during normal placental development. |
Mendeley readers
The data shown below were compiled from readership statistics for 61 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Mexico | 1 | 2% |
| Ukraine | 1 | 2% |
| Unknown | 58 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 20% |
| Researcher | 10 | 16% |
| Student > Doctoral Student | 7 | 11% |
| Student > Bachelor | 6 | 10% |
| Student > Master | 6 | 10% |
| Other | 11 | 18% |
| Unknown | 9 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 23 | 38% |
| Agricultural and Biological Sciences | 13 | 21% |
| Biochemistry, Genetics and Molecular Biology | 8 | 13% |
| Nursing and Health Professions | 2 | 3% |
| Engineering | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 7 | 11% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 November 2014.
All research outputs
#6,377,613
of 22,660,862 outputs
Outputs from PLOS ONE
#76,349
of 193,497 outputs
Outputs of similar age
#30,740
of 98,841 outputs
Outputs of similar age from PLOS ONE
#442
of 866 outputs
Altmetric has tracked 22,660,862 research outputs across all sources so far. This one has received more attention than most of these and is in the 70th percentile.
So far Altmetric has tracked 193,497 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 98,841 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.
We're also able to compare this research output to 866 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.