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Pain in Psychiatric Disorders

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Attention for Chapter: Visceral Pain and Psychiatric Disorders.
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Chapter title
Visceral Pain and Psychiatric Disorders.
Book title
Pain in Psychiatric Disorders
Published in
Modern trends in pharmacopsychiatry, September 2015
DOI 10.1159/000435936
Pubmed ID
Book ISBNs
978-3-31-805573-3, 978-3-31-805574-0
Authors

Felice, Valeria D, Moloney, Rachel D, Cryan, John F, Dinan, Timothy G, O'Mahony, Siobhain M, Felice, V.D., Moloney, R.D., Cryan, J.F., Dinan, T.G., O'Mahony, S.M., Valeria D. Felice, Rachel D. Moloney, John F. Cryan, Timothy G. Dinan, Siobhain M. O'Mahony, Siobhain M. O''Mahony

Abstract

The high comorbidity existing between visceral pain and psychiatric disorders such as depression and anxiety is well documented and it is gaining increasing interest among scientists. When visceral pain and psychiatric disorders are comorbid, they present a more debilitating condition than each disorder alone, impacting significantly on the quality of life of these patients. Despite several groups having shown that an overlapping pathophysiology exists between visceral pain and stress-related disorders the link between them is not clear yet. Moreover, it still remains to be elucidated if psychiatric conditions predispose the individual to develop visceral hypersensitivity or vice versa. The brain-gut-microbiome axis is the bidirectional communication between the CNS and the gastrointestinal tract. Alterations at different levels of this axis have been implicated in both visceral hypersensitivity and psychiatric disorders. Here we give an overview of what it is known about comorbid visceral pain and psychiatric disorders and provide evidence of potential overlapping pathophysiological mechanisms involved. Preclinical models of comorbid visceral pain and stress-related disorders are also discussed.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 55 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 55 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 9 16%
Student > Ph. D. Student 7 13%
Researcher 6 11%
Student > Master 6 11%
Student > Doctoral Student 6 11%
Other 13 24%
Unknown 8 15%
Readers by discipline Count As %
Medicine and Dentistry 17 31%
Agricultural and Biological Sciences 7 13%
Neuroscience 4 7%
Nursing and Health Professions 4 7%
Biochemistry, Genetics and Molecular Biology 3 5%
Other 9 16%
Unknown 11 20%