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Probing Electron Transport in Proteins at Room Temperature with Single-Molecule Precision

Overview of attention for article published in ACS Nano, December 2011
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Title
Probing Electron Transport in Proteins at Room Temperature with Single-Molecule Precision
Published in
ACS Nano, December 2011
DOI 10.1021/nn205016v
Pubmed ID
Authors

Michael S. Inkpen, Tim Albrecht

Abstract

Studying electron transport through immobilized proteins at the single-molecule level has been of interest for more than two decades, with a view on the fundamentals of charge transport in condensed media and applications in bioelectronics. Scanning tunneling microscopy (STM) is a powerful tool in this context, because, at least in principle, it should be possible to address individual proteins on an electrode surface reproducibly with single-protein precision. As reported in this issue of ACS Nano, MacDonald and colleagues have now achieved this for the first time at room temperature for covalently immobilized cytochrome b562, combining imaging and tunneling spectroscopy in a custom-built, ultralow drift STM, with single-protein precision. Using site-directed mutagenesis, cysteines introduced in specific locations in the amino acid sequence of the protein allowed the team to investigate conduction along different directions through the protein, namely along its short and long axes.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 32 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 6%
Canada 1 3%
Unknown 29 91%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 34%
Researcher 11 34%
Professor 4 13%
Student > Master 2 6%
Professor > Associate Professor 2 6%
Other 2 6%
Readers by discipline Count As %
Chemistry 15 47%
Physics and Astronomy 10 31%
Agricultural and Biological Sciences 2 6%
Unspecified 2 6%
Materials Science 2 6%
Other 1 3%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2012.
All research outputs
#2,901,708
of 3,628,883 outputs
Outputs from ACS Nano
#2,529
of 2,915 outputs
Outputs of similar age
#166,837
of 231,690 outputs
Outputs of similar age from ACS Nano
#123
of 152 outputs
Altmetric has tracked 3,628,883 research outputs across all sources so far. This one is in the 2nd percentile – i.e., 2% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,915 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 231,690 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 152 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.