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Intricate Knots in Proteins: Function and Evolution

Overview of attention for article published in PLoS Computational Biology, September 2006
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (91st percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

blogs
1 blog
twitter
1 X user
wikipedia
5 Wikipedia pages
video
1 YouTube creator

Citations

dimensions_citation
303 Dimensions

Readers on

mendeley
175 Mendeley
citeulike
1 CiteULike
connotea
2 Connotea
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Title
Intricate Knots in Proteins: Function and Evolution
Published in
PLoS Computational Biology, September 2006
DOI 10.1371/journal.pcbi.0020122
Pubmed ID
Authors

Peter Virnau, Leonid A Mirny, Mehran Kardar

Abstract

Our investigation of knotted structures in the Protein Data Bank reveals the most complicated knot discovered to date. We suggest that the occurrence of this knot in a human ubiquitin hydrolase might be related to the role of the enzyme in protein degradation. While knots are usually preserved among homologues, we also identify an exception in a transcarbamylase. This allows us to exemplify the function of knots in proteins and to suggest how they may have been created.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 175 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 3%
Germany 2 1%
Italy 2 1%
Spain 2 1%
Norway 1 <1%
Brazil 1 <1%
Canada 1 <1%
France 1 <1%
United Kingdom 1 <1%
Other 1 <1%
Unknown 158 90%

Demographic breakdown

Readers by professional status Count As %
Researcher 37 21%
Student > Ph. D. Student 36 21%
Student > Master 25 14%
Student > Bachelor 19 11%
Professor > Associate Professor 12 7%
Other 30 17%
Unknown 16 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 54 31%
Physics and Astronomy 30 17%
Chemistry 30 17%
Biochemistry, Genetics and Molecular Biology 19 11%
Computer Science 6 3%
Other 18 10%
Unknown 18 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 August 2021.
All research outputs
#3,212,427
of 25,374,647 outputs
Outputs from PLoS Computational Biology
#2,840
of 8,960 outputs
Outputs of similar age
#7,670
of 87,115 outputs
Outputs of similar age from PLoS Computational Biology
#7
of 34 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,960 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.4. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 87,115 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 91% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.