↓ Skip to main content

Amyloid-Mediated Sequestration of Essential Proteins Contributes to Mutant Huntingtin Toxicity in Yeast

Overview of attention for article published in PLOS ONE, January 2012
Altmetric Badge

About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

Mentioned by

wikipedia
4 Wikipedia pages

Citations

dimensions_citation
29 Dimensions

Readers on

mendeley
65 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Amyloid-Mediated Sequestration of Essential Proteins Contributes to Mutant Huntingtin Toxicity in Yeast
Published in
PLOS ONE, January 2012
DOI 10.1371/journal.pone.0029832
Pubmed ID
Authors

Natalia V. Kochneva-Pervukhova, Alexander I. Alexandrov, Michael D. Ter-Avanesyan

Abstract

Polyglutamine expansion is responsible for several neurodegenerative disorders, among which Huntington disease is the most well-known. Studies in the yeast model demonstrated that both aggregation and toxicity of a huntingtin (htt) protein with an expanded polyglutamine region strictly depend on the presence of the prion form of Rnq1 protein ([PIN+]), which has a glutamine/asparagine-rich domain.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
Israel 1 2%
Canada 1 2%
Korea, Republic of 1 2%
Russia 1 2%
Unknown 60 92%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 31%
Researcher 16 25%
Student > Bachelor 6 9%
Student > Master 6 9%
Professor 3 5%
Other 8 12%
Unknown 6 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 46%
Biochemistry, Genetics and Molecular Biology 20 31%
Chemistry 2 3%
Computer Science 1 2%
Psychology 1 2%
Other 4 6%
Unknown 7 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 April 2020.
All research outputs
#7,412,246
of 22,661,413 outputs
Outputs from PLOS ONE
#87,960
of 193,502 outputs
Outputs of similar age
#70,581
of 243,373 outputs
Outputs of similar age from PLOS ONE
#1,140
of 3,220 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,502 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,373 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,220 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.