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Characterization of the Endothelial Cell Cytoskeleton following HLA Class I Ligation

Overview of attention for article published in PLOS ONE, January 2012
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Title
Characterization of the Endothelial Cell Cytoskeleton following HLA Class I Ligation
Published in
PLOS ONE, January 2012
DOI 10.1371/journal.pone.0029472
Pubmed ID
Authors

Mary E. Ziegler, Puneet Souda, Yi-Ping Jin, Julian P. Whitelegge, Elaine F. Reed

Abstract

Vascular endothelial cells (ECs) are a target of antibody-mediated allograft rejection. In vitro, when the HLA class I molecules on the surface of ECs are ligated by anti-HLA class I antibodies, cell proliferation and survival pathways are activated and this is thought to contribute to the development of antibody-mediated rejection. Crosslinking of HLA class I molecules by anti-HLA antibodies also triggers reorganization of the cytoskeleton, which induces the formation of F-actin stress fibers. HLA class I induced stress fiber formation is not well understood.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 17%
Student > Ph. D. Student 5 17%
Student > Master 4 13%
Other 3 10%
Student > Doctoral Student 3 10%
Other 6 20%
Unknown 4 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 30%
Medicine and Dentistry 6 20%
Immunology and Microbiology 2 7%
Engineering 2 7%
Neuroscience 2 7%
Other 4 13%
Unknown 5 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 January 2012.
All research outputs
#18,303,566
of 22,661,413 outputs
Outputs from PLOS ONE
#153,766
of 193,502 outputs
Outputs of similar age
#194,812
of 243,373 outputs
Outputs of similar age from PLOS ONE
#2,385
of 3,220 outputs
Altmetric has tracked 22,661,413 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,502 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 243,373 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,220 others from the same source and published within six weeks on either side of this one. This one is in the 9th percentile – i.e., 9% of its contemporaries scored the same or lower than it.