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Cell-Penetrating Peptides

Overview of attention for book
Cover of 'Cell-Penetrating Peptides'

Table of Contents

  1. Altmetric Badge
    Book Overview
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    Chapter 1 Classes of Cell-Penetrating Peptides.
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    Chapter 2 Cell-Penetrating Peptides
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    Chapter 3 Prediction of Cell-Penetrating Peptides
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    Chapter 4 Computer-Aided Virtual Screening and Designing of Cell-Penetrating Peptides.
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    Chapter 5 Investigating Membrane Interactions and Structures of CPPs.
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    Chapter 6 Determining the Effects of Membrane-Interacting Peptides on Membrane Integrity.
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    Chapter 7 Study of CPP Mechanisms by Mass Spectrometry.
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    Chapter 8 Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides
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    Chapter 9 Toxicity, Immunogenicity, Uptake, and Kinetics Methods for CPPs
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    Chapter 10 Unraveling the Mechanisms of Peptide-Mediated Delivery of Nucleic Acids Using Electron Microscopy.
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    Chapter 11 SCARA Involvement in the Uptake of Nanoparticles Formed by Cell-Penetrating Peptides
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    Chapter 12 Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides.
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    Chapter 13 Pepducins and Other Lipidated Peptides as Mechanistic Probes and Therapeutics.
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    Chapter 14 Identification and Characterization of Homing Peptides Using In Vivo Peptide Phage Display.
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    Chapter 15 The Antimicrobial and Antiviral Applications of Cell-Penetrating Peptides
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    Chapter 16 Visualizing Actin Architectures in Cells Incubated with Cell-Penetrating Peptides.
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    Chapter 17 Cell-Penetrating Peptides as Carriers for Transepithelial Drug Delivery In Vitro.
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    Chapter 18 A Pathway Toward Tumor Cell-Selective CPPs?
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    Chapter 19 PepFects and NickFects for the Intracellular Delivery of Nucleic Acids
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    Chapter 20 In Vitro Assays to Assess Exon Skipping in Duchenne Muscular Dystrophy.
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    Chapter 21 Applications of ApoB LDLR-Binding Domain Approach for the Development of CNS-Penetrating Peptides for Alzheimer's Disease.
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    Chapter 22 CPP-Based Delivery System for In Vivo Gene Delivery
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    Chapter 23 Application of CPPs for Brain Delivery
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    Chapter 24 Intracellular Delivery of Nanoparticles with Cell Penetrating Peptides.
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    Chapter 25 Cell-Penetrating Peptides
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    Chapter 26 Cell Penetrating Peptides for Chemical Biological Studies.
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    Chapter 27 Experiences with CPP-Based Self Assembling Peptide Systems for Topical Delivery of Botulinum Toxin.
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    Chapter 28 Applications of CPPs in Genome Modulation of Plants.
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    Chapter 29 DNA Transfer into Animal Cells Using Stearylated CPP Based Transfection Reagent.
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    Chapter 30 Live Cell Genomics: Cell-Specific Transcriptome Capture in Live Tissues and Cells.
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    Chapter 31 Live Cell Genomics: RNA Exon-Specific RNA-Binding Protein Isolation.
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    Chapter 32 ERRATUM TO: Methods to Study the Role of the Glycocalyx in the Uptake of Cell-Penetrating Peptides.
Attention for Chapter 25: Cell-Penetrating Peptides
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Chapter title
Cell-Penetrating Peptides
Chapter number 25
Book title
Cell-Penetrating Peptides
Published in
Methods in molecular biology, January 2015
DOI 10.1007/978-1-4939-2806-4_25
Pubmed ID
26202283
Book ISBNs
978-1-4939-2805-7, 978-1-4939-2806-4
Authors

Weber, Judith, Lächelt, Ulrich, Wagner, Ernst, Judith Weber, Ulrich Lächelt, Ernst Wagner

Editors

Ülo Langel

Abstract

Drugs with novel and versatile modes of action, such as therapeutic nucleic acids or proteins, open new possibilities for the precise therapy of different diseases. The most crucial limitation during the development of a therapeutic drug remains the safe and efficient intracellular delivery.To overcome the hurdles and to realize the successful delivery of such new biopharmaceuticals, our laboratory has recently developed a sequence-defined, cationic oligomer platform based on solid-phase synthesis. These multifunctional oligomers have displayed efficient delivery of therapeutic RNA in vitro and in vivo. In this chapter, we provide a brief background on the special features and applications of these carrier systems as well as detailed protocols for the oligomer and polyplex synthesis and their evaluation.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
 Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 31%
Researcher 4 25%
Lecturer 3 19%
Student > Master 1 6%
Professor 1 6%
Other 0 0%
Unknown 2 13%
Readers by discipline Count As %
Chemistry 5 31%
Pharmacology, Toxicology and Pharmaceutical Science 3 19%
Agricultural and Biological Sciences 3 19%
Nursing and Health Professions 1 6%
Medicine and Dentistry 1 6%
Other 1 6%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2016.
All research outputs
#18,453,763
of 22,865,319 outputs
Outputs from Methods in molecular biology
#7,923
of 13,127 outputs
Outputs of similar age
#256,040
of 353,293 outputs
Outputs of similar age from Methods in molecular biology
#481
of 997 outputs
Altmetric has tracked 22,865,319 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,127 research outputs from this source. They receive a mean Attention Score of 3.4. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
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We're also able to compare this research output to 997 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.

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