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Target Identification and Validation in Drug Discovery

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Cover of 'Target Identification and Validation in Drug Discovery'

Table of Contents

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    Book Overview
  2. Altmetric Badge
    Chapter 1 Why High-Performance Modelling and Simulation for Big Data Applications Matters
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    Chapter 1 Using Functional Genetics in Haploid Cells for Drug Target Identification
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    Chapter 1 Critical Infrastructure
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    Chapter 2 Unbiased Forward Genetic Screening with Chemical Mutagenesis to Uncover Drug–Target Interactions
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    Chapter 2 Parallelization of Hierarchical Matrix Algorithms for Electromagnetic Scattering Problems
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    Chapter 2 Critical Space Infrastructures
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    Chapter 3 Integration of RNAi and Small Molecule Screens to Identify Targets for Drug Development
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    Chapter 3 Critical Space Infrastructure Taxonomy
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    Chapter 3 Tail Distribution and Extreme Quantile Estimation Using Non-parametric Approaches
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    Chapter 4 Towards Efficient and Scalable Data-Intensive Content Delivery: State-of-the-Art, Issues and Challenges
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    Chapter 4 Critical Space Infrastructure Interdependencies
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    Chapter 4 CellProfiler and KNIME: Open-Source Tools for High-Content Screening
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    Chapter 5 Big Data in 5G Distributed Applications
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    Chapter 5 National and Global Effects—Malfunction and Destruction of CSI
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    Chapter 5 In Silico Target Druggability Assessment: From Structural to Systemic Approaches
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    Chapter 6 Big Data Processing, Analysis and Applications in Mobile Cellular Networks
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    Chapter 6 Critical Space Infrastructure Protection
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    Chapter 6 In Silico Drug–Target Profiling
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    Chapter 7 Medical Data Processing and Analysis for Remote Health and Activities Monitoring
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    Chapter 7 Crisis and Emergency Situation Management
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    Chapter 7 Locus-Specific Knock-In of a Degradable Tag for Target Validation Studies
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    Chapter 8 Serious Gaming and Policy Gaming
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    Chapter 8 Expression of Human VH Single Domains as Fc Fusions in Mammalian Cells
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    Chapter 8 Towards Human Cell Simulation
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    Chapter 9 Space Capabilities—A Critical Tool for Nuclear Issues
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    Chapter 9 Cloud-Based High Throughput Virtual Screening in Novel Drug Discovery
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    Chapter 9 The Neurosphere Assay (NSA) Applied to Neural Stem Cells (NSCs) and Cancer Stem Cells (CSCs)
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    Chapter 10 Governance by Emerging Technologies—The Case for Sand and Blockchain Technology
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    Chapter 10 Ultra Wide Band Body Area Networks: Design and Integration with Computational Clouds
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    Chapter 10 3D-3 Tumor Models in Drug Discovery for Analysis of Immune Cell Infiltration
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    Chapter 11 Establishing Governance for CSI: An MCDA Approach
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    Chapter 11 Survey on AI-Based Multimodal Methods for Emotion Detection
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    Chapter 11 Establishment and Analysis of a 3D Co-Culture Spheroid Model of Pancreatic Adenocarcinoma for Application in Drug Discovery
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    Chapter 12 CSI—A Complex System Governance Approach
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    Chapter 12 Forecasting Cryptocurrency Value by Sentiment Analysis: An HPC-Oriented Survey of the State-of-the-Art in the Cloud Era
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    Chapter 12 In Vivo Pharmacology Models for Cancer Target Research
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    Chapter 13 Use of CRISPR/Cas9 for the Modification of the Mouse Genome
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    Chapter 13 CSG: Towards CSI Research
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    Chapter 14 Assessment of Gene Function of Mouse Innate Lymphoid Cells for In Vivo Analysis Using Retroviral Transduction
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    Chapter 15 Creation of PDX-Bearing Humanized Mice to Study Immuno-oncology
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    Chapter 16 Immunophenotyping of Tissue Samples Using Multicolor Flow Cytometry
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    Chapter 17 Combined MicroRNA In Situ Hybridization and Immunohistochemical Detection of Protein Markers
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    Chapter 18 Tangential Flow Filtration with or Without Subsequent Bind-Elute Size Exclusion Chromatography for Purification of Extracellular Vesicles
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    Chapter 19 Chromogenic Tissue-Based Methods for Detection of Gene Amplifications (or Rearrangements) Combined with Protein Overexpression in Clinical Samples
Attention for Chapter 12: Forecasting Cryptocurrency Value by Sentiment Analysis: An HPC-Oriented Survey of the State-of-the-Art in the Cloud Era
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Chapter title
Forecasting Cryptocurrency Value by Sentiment Analysis: An HPC-Oriented Survey of the State-of-the-Art in the Cloud Era
Chapter number 12
Book title
Target Identification and Validation in Drug Discovery
Published by
Springer, Cham, March 2019
DOI 10.1007/978-3-030-16272-6_12
Book ISBNs
978-1-4939-9144-0, 978-1-4939-9145-7, 978-3-03-016271-9, 978-3-03-016272-6
Authors

Aleš Zamuda, Vincenzo Crescimanna, Juan C. Burguillo, Joana Matos Dias, Katarzyna Wegrzyn-Wolska, Imen Rached, Horacio González-Vélez, Roman Senkerik, Claudia Pop, Tudor Cioara, Ioan Salomie, Andrea Bracciali

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 16%
Student > Master 3 16%
Student > Doctoral Student 3 16%
Lecturer 2 11%
Student > Ph. D. Student 2 11%
Other 3 16%
Unknown 3 16%
Readers by discipline Count As %
Computer Science 7 37%
Business, Management and Accounting 2 11%
Economics, Econometrics and Finance 2 11%
Linguistics 1 5%
Engineering 1 5%
Other 1 5%
Unknown 5 26%