Title |
Melatonin receptor 1 B polymorphisms associated with the risk of gestational diabetes mellitus
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Published in |
BMC Medical Genomics, June 2011
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DOI | 10.1186/1471-2350-12-82 |
Pubmed ID | |
Authors |
Jason Y Kim, Hyun Sub Cheong, Byung-Lae Park, Sei Hyun Baik, Sunmin Park, Si Won Lee, Min-Hyoung Kim, Jin Hoon Chung, June Seek Choi, Moon-Young Kim, Jae-Hyug Yang, Dong-Hee Cho, Hyoung Doo Shin, Sung-Hoon Kim |
Abstract |
Two SNPs in melatonin receptor 1B gene, rs10830963 and rs1387153 showed significant associations with fasting plasma glucose levels and the risk of Type 2 Diabetes Mellitus (T2DM) in previous studies. Since T2DM and gestational diabetes mellitus (GDM) share similar characteristics, we suspected that the two genetic polymorphisms in MTNR1B may be associated with GDM, and conducted association studies between the polymorphisms and the disease. Furthermore, we also examined genetic effects of the two polymorphisms with various diabetes-related phenotypes. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 2% |
India | 1 | 2% |
Unknown | 60 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 10 | 16% |
Student > Bachelor | 9 | 15% |
Student > Ph. D. Student | 9 | 15% |
Student > Master | 9 | 15% |
Student > Postgraduate | 7 | 11% |
Other | 11 | 18% |
Unknown | 7 | 11% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 21 | 34% |
Agricultural and Biological Sciences | 12 | 19% |
Biochemistry, Genetics and Molecular Biology | 7 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 8% |
Nursing and Health Professions | 1 | 2% |
Other | 5 | 8% |
Unknown | 11 | 18% |