Identification of a Functional Non-coding Variant in the GABAA Receptor α2 Subunit of the C57BL/6J Mouse Reference Genome: Major Implications for Neuroscience Research

That one is minor compared to COMT and GABRA2. COMT mutation in B6: https://t.co/nuHz62XSE7 GABRA2 mutation in this paper: https://t.co/WYJWOlwdxf @M2Longhorn @PessoaBrain @WiringTheBrain

And it has a unique de novo mutation in Gabra2—not an unimportant gene. ;-). One of many other variants and mutations. Of course every inbred strain carries its own unique load of mutations—just as each of us. @M2Longhorn @CamronBryantPhD @DavidAshbrook

RT @robwilliamsiii: Define "wildtype mouse"? 01. Definition: "A mouse with about 100 knockouts and 500 knockdown mutations that YOU happen…

@GeneNetwork2 @ICDAbio @ceclindgren @woychiklab