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A Role for VEGFR2 Activation in Endothelial Responses Caused by Barrier Disruptive OxPAPC Concentrations

Overview of attention for article published in PLOS ONE, January 2012
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2 X users

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Title
A Role for VEGFR2 Activation in Endothelial Responses Caused by Barrier Disruptive OxPAPC Concentrations
Published in
PLOS ONE, January 2012
DOI 10.1371/journal.pone.0030957
Pubmed ID
Authors

Anna A. Birukova, Sangderk Lee, Vitaliy Starosta, Tinghuai Wu, Tiffany Ho, Jin Kim, Judith A. Berliner, Konstantin G. Birukov

Abstract

Oxidation products of 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphatidylcholine (OxPAPC) differentially modulate endothelial cell (EC) barrier function in a dose-dependent fashion. Vascular endothelial growth factor receptor-2 (VEGFR2) is involved in the OxPAPC-induced EC inflammatory activation. This study examined a role of VEGFR2 in barrier dysfunction caused by high concentrations of OxPAPC and evaluated downstream signaling mechanisms resulting from the effect of OxPAPC in EC from pulmonary and systemic circulation.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 14%
Researcher 4 14%
Student > Master 4 14%
Other 3 11%
Student > Postgraduate 2 7%
Other 4 14%
Unknown 7 25%
Readers by discipline Count As %
Medicine and Dentistry 6 21%
Agricultural and Biological Sciences 5 18%
Biochemistry, Genetics and Molecular Biology 3 11%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Chemistry 2 7%
Other 3 11%
Unknown 7 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2012.
All research outputs
#17,655,049
of 22,662,201 outputs
Outputs from PLOS ONE
#146,214
of 193,504 outputs
Outputs of similar age
#191,961
of 247,129 outputs
Outputs of similar age from PLOS ONE
#2,377
of 3,365 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,504 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,129 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3,365 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.