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Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory Pathways

Overview of attention for article published in PLOS ONE, April 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (95th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

blogs
2 blogs
patent
5 patents
wikipedia
2 Wikipedia pages

Readers on

mendeley
69 Mendeley
citeulike
2 CiteULike
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Title
Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory Pathways
Published in
PLOS ONE, April 2009
DOI 10.1371/journal.pone.0005242
Pubmed ID
Authors

Preston Wayne Estep, Jason B. Warner, Martha L. Bulyk

Abstract

Calorie restriction (CR) is the only intervention known to extend lifespan in a wide range of organisms, including mammals. However, the mechanisms by which it regulates mammalian aging remain largely unknown, and the involvement of the TOR and sirtuin pathways (which regulate aging in simpler organisms) remain controversial. Additionally, females of most mammals appear to live longer than males within species; and, although it remains unclear whether this holds true for mice, the relationship between sex-biased and CR-induced gene expression remains largely unexplored.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
United States 1 1%
Korea, Republic of 1 1%
Belarus 1 1%
Unknown 65 94%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 23%
Student > Ph. D. Student 15 22%
Student > Master 10 14%
Professor > Associate Professor 5 7%
Professor 5 7%
Other 9 13%
Unknown 9 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 31 45%
Biochemistry, Genetics and Molecular Biology 10 14%
Medicine and Dentistry 8 12%
Chemistry 2 3%
Neuroscience 2 3%
Other 5 7%
Unknown 11 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 21. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2021.
All research outputs
#1,799,693
of 25,837,817 outputs
Outputs from PLOS ONE
#21,921
of 224,660 outputs
Outputs of similar age
#4,625
of 98,265 outputs
Outputs of similar age from PLOS ONE
#70
of 517 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 224,660 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.8. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 98,265 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 517 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.