Title |
Subcutaneous adipose tissue fatty acid desaturation in adults with and without rare adipose disorders
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Published in |
Lipids in Health and Disease, February 2012
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DOI | 10.1186/1476-511x-11-19 |
Pubmed ID | |
Authors |
Jennifer K Yee, Susan A Phillips, Kambiz Allamehzadeh, Karen L Herbst |
Abstract |
Elevated stearoyl-CoA desaturase activity has been described in obese states, with an increased desaturation index (DI) suggesting enhanced lipogenesis. Differences in the DI among various phenotypes of abnormal adiposity have not been studied. Abnormal accumulation of subcutaneous adipose tissue occurs in rare adipose disorders (RADs) including Dercum's disease (DD), multiple symmetric lipomatosis (MSL), and familial multiple lipomatosis (FML). Examining the DI in subcutaneous fat of people with DD, MSL and FML may provide information on adipose tissue fatty acid metabolism in these disorders. The aims of this pilot study were: 1) to determine if differences in adipose tissue DIs are present among RADs, and 2) to determine if the DIs correlate to clinical or biochemical parameters. |
X Demographics
Geographical breakdown
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Chile | 1 | 3% |
Unknown | 28 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 6 | 21% |
Student > Ph. D. Student | 4 | 14% |
Student > Master | 4 | 14% |
Student > Bachelor | 3 | 10% |
Professor > Associate Professor | 3 | 10% |
Other | 6 | 21% |
Unknown | 3 | 10% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 38% |
Agricultural and Biological Sciences | 6 | 21% |
Biochemistry, Genetics and Molecular Biology | 4 | 14% |
Sports and Recreations | 2 | 7% |
Engineering | 2 | 7% |
Other | 0 | 0% |
Unknown | 4 | 14% |