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Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis

Overview of attention for article published in Arthritis Research & Therapy, February 2012
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Citations

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214 Mendeley
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Title
Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis
Published in
Arthritis Research & Therapy, February 2012
DOI 10.1186/ar3735
Pubmed ID
Authors

Mitsuhiko Sato, Kenzo Uchida, Hideaki Nakajima, Tsuyoshi Miyazaki, Alexander Rodriguez Guerrero, Shuji Watanabe, Sally Roberts, Hisatoshi Baba

Abstract

Mesenchymal stem cells (MSCs) can differentiate into various connective tissue cells. Several techniques have been used for the clinical application of MSCs in articular cartilage repair; however, there are many issues associated with the selection of the scaffold material, including its ability to support cell viability and differentiation and its retention and degradation in situ. The application of MSCs via a scaffold also requires a technically demanding surgical procedure. The aim of this study was to test the outcome of intra-articular transplantation of mesenchymal stem cells suspended in hyaluronic acid (HA) in the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis (OA).

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 214 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 2 <1%
France 2 <1%
United States 1 <1%
Unknown 209 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 41 19%
Student > Master 26 12%
Student > Ph. D. Student 24 11%
Student > Bachelor 24 11%
Student > Postgraduate 18 8%
Other 38 18%
Unknown 43 20%
Readers by discipline Count As %
Medicine and Dentistry 59 28%
Biochemistry, Genetics and Molecular Biology 34 16%
Agricultural and Biological Sciences 32 15%
Engineering 10 5%
Veterinary Science and Veterinary Medicine 7 3%
Other 25 12%
Unknown 47 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2012.
All research outputs
#17,285,668
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#2,536
of 3,381 outputs
Outputs of similar age
#172,990
of 253,980 outputs
Outputs of similar age from Arthritis Research & Therapy
#41
of 61 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,980 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 61 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.