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Transmission dynamics of HIV-1 subtype B in the Basque country, Spain

Overview of attention for article published in Infection, Genetics & Evolution, February 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (71st percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

9 tweeters
1 Facebook page


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8 Mendeley
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Transmission dynamics of HIV-1 subtype B in the Basque country, Spain
Published in
Infection, Genetics & Evolution, February 2016
DOI 10.1016/j.meegid.2016.02.028
Pubmed ID

Patiño-Galindo, J A, Thomson, Michael M, Pérez-Álvarez, Lucía, Delgado, Elena, Cuevas, María Teresa, Fernández-García, Aurora, Nájera, Rafael, Iribarren, José A, Cilla, Gustavo, López-Soria, Leyre, Lezaun, María J, Cisterna, Ramón, González-Candelas, F, , , J.A. Patiño-Galindo, Michael M. Thomson, Lucía Pérez-Álvarez, Elena Delgado, María Teresa Cuevas, Aurora Fernández-García, Rafael Nájera, José A. Iribarren, Gustavo Cilla, Leyre López-Soria, María J. Lezaun, Ramón Cisterna, F. González-Candelas


This work was aimed to study the HIV-1 subtype B epidemics in the Basque Country, Spain. 1727 HIV-1 subtype B sequences comprising protease and reverse transcriptase (PR/RT) coding regions, sampled between 2001 and 2008, were analyzed. 156 transmission clusters were detected by means of phylogenetic analyses. Most of them comprised less than 4 individuals and, in total, they included 441 patients. Six clusters comprised 10 or more patients and were further analyzed in order to study their origin and diversification. Four clusters included men who had unprotected homosexual sex (MSM), one group was formed by intravenous drug users (IDUs), and another included both IDUs and people infected through unprotected heterosexual sex (HTs). Most of these clusters originated from the mid-1980s to the mid-1990s. Only one cluster, formed by MSM, originated after 2000. The time between infections was significantly lower in MSM groups than in those containing IDUs (P-value <0.0001). Nucleoside RT and non-nucleoside RT inhibitor (NRTI and NNRTI)-resistance mutations to antiretroviral treatment were found in these six clusters except the most recent MSM group, but only the IDU clusters presented protease inhibitor (PI)-resistance mutations. The most prevalent mutations for each inhibitor class were PI L90M, NRTI T215D/Y/F, and NNRTI K103N, which were also among the most prevalent resistant variants in the whole dataset. In conclusion, while most infections occur as isolated introductions into the population, the number of infections found to be epidemiologically related within the Basque Country is significant. Public health control measures should be reinforced to prevent the further expansion of transmission clusters and resistant mutations occurring within them.

Twitter Demographics

The data shown below were collected from the profiles of 9 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Professor 2 25%
Student > Bachelor 2 25%
Student > Master 2 25%
Researcher 2 25%
Student > Postgraduate 1 13%
Other 2 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 63%
Unspecified 2 25%
Biochemistry, Genetics and Molecular Biology 1 13%
Nursing and Health Professions 1 13%
Environmental Science 1 13%
Other 1 13%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2017.
All research outputs
of 11,505,507 outputs
Outputs from Infection, Genetics & Evolution
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Outputs of similar age
of 292,005 outputs
Outputs of similar age from Infection, Genetics & Evolution
of 84 outputs
Altmetric has tracked 11,505,507 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,720 research outputs from this source. They receive a mean Attention Score of 2.5. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 292,005 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.