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Androgen receptor signalling in Vascular Endothelial cells is dispensable for spermatogenesis and male fertility

Overview of attention for article published in BMC Research Notes, January 2012
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Title
Androgen receptor signalling in Vascular Endothelial cells is dispensable for spermatogenesis and male fertility
Published in
BMC Research Notes, January 2012
DOI 10.1186/1756-0500-5-16
Pubmed ID
Authors

Laura O'Hara, Lee B Smith

Abstract

Androgen signalling is essential both for male development and function of the male reproductive system in adulthood. Within the adult testis, Germ cells (GC) do not express androgen receptor (AR) suggesting androgen-mediated promotion of spermatogenesis must act via AR-expressing somatic cell-types. Several recent studies have exploited the Cre/lox system of conditional gene-targeting to ablate AR function from key somatic cell-types in order to establish the cell-specific role of AR in promotion of male fertility. In this study, we have used a similar approach to specifically ablate AR-signalling from Vascular Endothelial (VE) cells, with a view to defining the significance of androgen signalling within this cell-type on spermatogenesis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 21 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 5%
Unknown 20 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 29%
Student > Doctoral Student 3 14%
Student > Bachelor 2 10%
Researcher 2 10%
Student > Ph. D. Student 2 10%
Other 2 10%
Unknown 4 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 9 43%
Biochemistry, Genetics and Molecular Biology 4 19%
Veterinary Science and Veterinary Medicine 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Nursing and Health Professions 1 5%
Other 1 5%
Unknown 4 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 January 2012.
All research outputs
#20,155,513
of 22,663,150 outputs
Outputs from BMC Research Notes
#3,544
of 4,248 outputs
Outputs of similar age
#219,818
of 242,753 outputs
Outputs of similar age from BMC Research Notes
#76
of 81 outputs
Altmetric has tracked 22,663,150 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,248 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 242,753 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.