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Progesterone administration for luteal phase deficiency in human reproduction: an old or new issue?

Overview of attention for article published in Journal of Ovarian Research, November 2015
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About this Attention Score

  • Among the highest-scoring outputs from this source (#46 of 360)
  • Good Attention Score compared to outputs of the same age (69th percentile)

Mentioned by

1 tweeter
1 Facebook page
1 Wikipedia page


26 Dimensions

Readers on

59 Mendeley
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Progesterone administration for luteal phase deficiency in human reproduction: an old or new issue?
Published in
Journal of Ovarian Research, November 2015
DOI 10.1186/s13048-015-0205-8
Pubmed ID

Stefano Palomba, Susanna Santagni, Giovanni Battista La Sala


Luteal phase deficiency (LPD) is described as a condition of insufficient progesterone exposure to maintain a regular secretory endometrium and allow for normal embryo implantation and growth. Recently, scientific focus is turning to understand the physiology of implantation, in particular the several molecular markers of endometrial competence, through the recent transcriptomic approaches and microarray technology. In spite of the wide availability of clinical and instrumental methods for assessing endometrial competence, reproducible and reliable diagnostic tests for LPD are currently lacking, so no type-IA evidence has been proposed by the main scientific societies for assessing endometrial competence in infertile couples. Nevertheless, LPD is a very common condition that may occur during a series of clinical conditions, and during controlled ovarian stimulation (COS) and hyperstimulation (COH) programs. In many cases, the correct approach to treat LPD is the identification and correction of any underlying condition while, in case of no underlying dysfunction, the treatment becomes empiric. To date, no direct data is available regarding the efficacy of luteal phase support for improving fertility in spontaneous cycles or in non-gonadotropin induced ovulatory cycles. On the contrary, in gonadotropin in vitro fertilization (IVF) and non-IVF cycles, LPD is always present and progesterone exerts a significant positive effect on reproductive outcomes. The scientific debate still remains open regarding progesterone administration protocols, specially on routes of administration, dose and timing and the potential association with other drugs, and further research is still needed.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ghana 1 2%
Unknown 58 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 19%
Researcher 8 14%
Student > Bachelor 6 10%
Student > Doctoral Student 6 10%
Other 5 8%
Other 16 27%
Unknown 7 12%
Readers by discipline Count As %
Medicine and Dentistry 31 53%
Agricultural and Biological Sciences 4 7%
Biochemistry, Genetics and Molecular Biology 4 7%
Nursing and Health Professions 4 7%
Immunology and Microbiology 2 3%
Other 5 8%
Unknown 9 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 May 2020.
All research outputs
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Outputs from Journal of Ovarian Research
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Outputs of similar age
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Outputs of similar age from Journal of Ovarian Research
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Altmetric has tracked 15,566,403 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 360 research outputs from this source. They receive a mean Attention Score of 2.7. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 268,743 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them