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Evidence-based review of oral traditional Chinese medicine compound recipe administration for treating weight drop-induced experimental traumatic brain injury

Overview of attention for article published in BMC Complementary and Alternative Medicine, March 2016
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1 tweeter

Citations

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10 Dimensions

Readers on

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14 Mendeley
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Title
Evidence-based review of oral traditional Chinese medicine compound recipe administration for treating weight drop-induced experimental traumatic brain injury
Published in
BMC Complementary and Alternative Medicine, March 2016
DOI 10.1186/s12906-016-1076-2
Pubmed ID
Authors

Bo Yang, Zhe Wang, Chenxia Sheng, Yang Wang, Jing Zhou, Xin-gui Xiong, Weijun Peng

Abstract

Recently, a number of studies conducted and published in China have suggested that traditional Chinese medicine compound recipe (TCMCR) may be beneficial in the treatment of experimental traumatic brain injury (TBI). In this study, we conducted a systematic review and meta-analysis of the efficacy of TCMCR in TBI model with weight drop method to provide robust evidence on the effects of TCMCR and to determine whether TCMCR can be recommended for routine treatment or considered as a standard treatment for TBI. We identified eligible studies by searching five electronic databases on April 1, 2014, and pooled the data using the random-effects model. Results were reported in terms of standardized mean difference (SMD). We also calculated statistical heterogeneity, evaluated the studies' methodological quality and investigated the presence of publication bias. Totally, 187 relevant publications were searched from databases, 25 of which met our inclusion criteria. The overall methodological quality of the most studies was poor, and there was evidence of statistical heterogeneity among studies along with small-study effects. Meta-analysis showed statistically significant effects indicating that TCMCR has a beneficial effect on TBI. Despite the limitations, we concluded that TCMCR may reduce brain water content, improve BBB permeability, and decrease TNF-α/NO expression after experimental TBI in terms of overall efficacy. However, our review also indicates that more well-designed and well-reported animal studies are needed.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 14 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 29%
Student > Doctoral Student 3 21%
Researcher 1 7%
Student > Master 1 7%
Unknown 5 36%
Readers by discipline Count As %
Medicine and Dentistry 2 14%
Psychology 2 14%
Agricultural and Biological Sciences 2 14%
Nursing and Health Professions 1 7%
Biochemistry, Genetics and Molecular Biology 1 7%
Other 1 7%
Unknown 5 36%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2016.
All research outputs
#3,786,165
of 7,377,175 outputs
Outputs from BMC Complementary and Alternative Medicine
#1,042
of 1,817 outputs
Outputs of similar age
#150,751
of 278,481 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#24
of 62 outputs
Altmetric has tracked 7,377,175 research outputs across all sources so far. This one is in the 28th percentile – i.e., 28% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,817 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.3. This one is in the 31st percentile – i.e., 31% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,481 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 62 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.