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Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovary

Overview of attention for article published in Reproductive Biology and Endocrinology, February 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (80th percentile)
  • High Attention Score compared to outputs of the same age and source (83rd percentile)

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8 X users

Citations

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126 Dimensions

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Title
Resveratrol promotes expression of SIRT1 and StAR in rat ovarian granulosa cells: an implicative role of SIRT1 in the ovary
Published in
Reproductive Biology and Endocrinology, February 2012
DOI 10.1186/1477-7827-10-14
Pubmed ID
Authors

Yoshihiro Morita, Osamu Wada-Hiraike, Tetsu Yano, Akira Shirane, Mana Hirano, Haruko Hiraike, Satoshi Koyama, Hajime Oishi, Osamu Yoshino, Yuichiro Miyamoto, Kenbun Sone, Katsutoshi Oda, Shunsuke Nakagawa, Kazuyoshi Tsutsui, Yuji Taketani

Abstract

Resveratrol is a natural polyphenolic compound known for its beneficial effects on energy homeostasis, and it also has multiple properties, including anti-oxidant, anti-inflammatory, and anti-tumor activities. Recently, silent information regulator genes (Sirtuins) have been identified as targets of resveratrol. Sirtuin 1 (SIRT1), originally found as an NAD+-dependent histone deacetylase, is a principal modulator of pathways downstream of calorie restriction, and the activation of SIRT1 ameliorates glucose homeostasis and insulin sensitivity. To date, the presence and physiological role of SIRT1 in the ovary are not known. Here we found that SIRT1 was localized in granulosa cells of the human ovary.

X Demographics

X Demographics

The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 2%
Portugal 1 1%
France 1 1%
Belarus 1 1%
Unknown 88 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 17%
Student > Ph. D. Student 13 14%
Student > Master 9 10%
Student > Bachelor 9 10%
Professor > Associate Professor 8 9%
Other 21 23%
Unknown 17 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 25%
Biochemistry, Genetics and Molecular Biology 19 20%
Medicine and Dentistry 14 15%
Pharmacology, Toxicology and Pharmaceutical Science 3 3%
Engineering 2 2%
Other 9 10%
Unknown 23 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2013.
All research outputs
#4,735,071
of 23,653,937 outputs
Outputs from Reproductive Biology and Endocrinology
#186
of 1,015 outputs
Outputs of similar age
#29,897
of 158,182 outputs
Outputs of similar age from Reproductive Biology and Endocrinology
#2
of 6 outputs
Altmetric has tracked 23,653,937 research outputs across all sources so far. Compared to these this one has done well and is in the 79th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,015 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.3. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 158,182 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.