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Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial

Overview of attention for article published in Trials, February 2012
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Title
Efficacy of early neonatal vitamin A supplementation in reducing mortality during infancy in Ghana, India and Tanzania: study protocol for a randomized controlled trial
Published in
Trials, February 2012
DOI 10.1186/1745-6215-13-22
Pubmed ID
Authors

NEOVITA Study Author Group, Rajiv Bahl, Nita Bhandari, Brinda Dube, Karen Edmond, Wafaie Fawzi, Olivier Fontaine, Jasmine Kaur, Betty R Kirkwood, Jose Martines, Honorati Masanja, Sarmila Mazumder, Salum Msham, Sam Newton, Maureen Oleary, Julia Ruben, Caitlin Shannon, Emily Smith, Sunita Taneja, Sachiyo Yoshida

Abstract

Vitamin A supplementation of 6-59 month old children is currently recommended by the World Health Organization based on evidence that it reduces mortality. There has been considerable interest in determining the benefits of neonatal vitamin A supplementation, but the results of existing trials are conflicting. A technical consultation convened by WHO pointed to the need for larger scale studies in Asia and Africa to inform global policy on the use of neonatal vitamin A supplementation. Three trials were therefore initiated in Ghana, India and Tanzania to determine if vitamin A supplementation (50,000 IU) given to neonates once orally on the day of birth or within the next two days will reduce mortality in the period from supplementation to 6 months of age compared to placebo.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 154 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Peru 1 <1%
Niger 1 <1%
Tanzania, United Republic of 1 <1%
Unknown 150 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 29 19%
Student > Master 26 17%
Student > Ph. D. Student 14 9%
Student > Postgraduate 13 8%
Student > Bachelor 12 8%
Other 19 12%
Unknown 41 27%
Readers by discipline Count As %
Medicine and Dentistry 48 31%
Social Sciences 15 10%
Nursing and Health Professions 13 8%
Agricultural and Biological Sciences 12 8%
Biochemistry, Genetics and Molecular Biology 5 3%
Other 16 10%
Unknown 45 29%