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Isothermal Amplification Using a Chemical Heating Device for Point-of-Care Detection of HIV-1

Overview of attention for article published in PLOS ONE, February 2012
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

Mentioned by

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3 X users
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4 patents

Citations

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112 Dimensions

Readers on

mendeley
203 Mendeley
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1 CiteULike
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Title
Isothermal Amplification Using a Chemical Heating Device for Point-of-Care Detection of HIV-1
Published in
PLOS ONE, February 2012
DOI 10.1371/journal.pone.0031432
Pubmed ID
Authors

Kelly A. Curtis, Donna L. Rudolph, Irene Nejad, Jered Singleton, Andy Beddoe, Bernhard Weigl, Paul LaBarre, S. Michele Owen

Abstract

To date, the use of traditional nucleic acid amplification tests (NAAT) for detection of HIV-1 DNA or RNA has been restricted to laboratory settings due to time, equipment, and technical expertise requirements. The availability of a rapid NAAT with applicability for resource-limited or point-of-care (POC) settings would fill a great need in HIV diagnostics, allowing for timely diagnosis or confirmation of infection status, as well as facilitating the diagnosis of acute infection, screening and evaluation of infants born to HIV-infected mothers. Isothermal amplification methods, such as reverse-transcription, loop-mediated isothermal amplification (RT-LAMP), exhibit characteristics that are ideal for POC settings, since they are typically quicker, easier to perform, and allow for integration into low-tech, portable heating devices.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 203 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
Germany 1 <1%
Malaysia 1 <1%
South Africa 1 <1%
Brazil 1 <1%
Canada 1 <1%
Madagascar 1 <1%
Unknown 194 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 55 27%
Student > Ph. D. Student 44 22%
Student > Master 15 7%
Student > Bachelor 15 7%
Student > Postgraduate 10 5%
Other 29 14%
Unknown 35 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 47 23%
Engineering 38 19%
Biochemistry, Genetics and Molecular Biology 24 12%
Medicine and Dentistry 16 8%
Chemistry 6 3%
Other 26 13%
Unknown 46 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2022.
All research outputs
#4,323,333
of 24,631,014 outputs
Outputs from PLOS ONE
#51,585
of 212,891 outputs
Outputs of similar age
#25,662
of 160,158 outputs
Outputs of similar age from PLOS ONE
#718
of 3,525 outputs
Altmetric has tracked 24,631,014 research outputs across all sources so far. Compared to these this one has done well and is in the 82nd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 212,891 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.6. This one has gotten more attention than average, scoring higher than 66% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 160,158 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 3,525 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.