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Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies

Overview of attention for article published in Revista Brasileira de Psiquiatria, March 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • One of the highest-scoring outputs from this source (#9 of 432)
  • High Attention Score compared to outputs of the same age (94th percentile)

Mentioned by

news
1 news outlet
blogs
2 blogs
twitter
14 tweeters
facebook
10 Facebook pages
wikipedia
3 Wikipedia pages
video
3 video uploaders

Citations

dimensions_citation
67 Dimensions

Readers on

mendeley
265 Mendeley
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Title
Antidepressive and anxiolytic effects of ayahuasca: a systematic literature review of animal and human studies
Published in
Revista Brasileira de Psiquiatria, March 2016
DOI 10.1590/1516-4446-2015-1701
Pubmed ID
Authors

Rafael G. dos Santos, Flávia L. Osório, José Alexandre S. Crippa, Jaime E. C. Hallak

Abstract

To conduct a systematic literature review of animal and human studies reporting anxiolytic or antidepressive effects of ayahuasca or some of its isolated alkaloids (dimethyltryptamine, harmine, tetrahydroharmine, and harmaline). Papers published until 3 April 2015 were retrieved from the PubMed, LILACS and SciELO databases following a comprehensive search strategy and using a predetermined set of criteria for article selection. Five hundred and fourteen studies were identified, of which 21 met the established criteria. Studies in animals have shown anxiolytic and antidepressive effects of ayahuasca, harmine, and harmaline, and experimental studies in humans and mental health assessments of experienced ayahuasca consumers also suggest that ayahuasca is associated with reductions in anxiety and depressive symptoms. A pilot study reported rapid antidepressive effects of a single ayahuasca dose in six patients with recurrent depression. Considering the need for new drugs that produce fewer adverse effects and are more effective in reducing anxiety and depression symptomatology, the described effects of ayahuasca and its alkaloids should be further investigated.

Twitter Demographics

The data shown below were collected from the profiles of 14 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 265 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 <1%
Switzerland 1 <1%
Brazil 1 <1%
Finland 1 <1%
United Kingdom 1 <1%
Unknown 260 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 62 23%
Student > Master 55 21%
Researcher 25 9%
Student > Doctoral Student 25 9%
Student > Ph. D. Student 20 8%
Other 37 14%
Unknown 41 15%
Readers by discipline Count As %
Psychology 42 16%
Medicine and Dentistry 40 15%
Neuroscience 36 14%
Pharmacology, Toxicology and Pharmaceutical Science 32 12%
Agricultural and Biological Sciences 21 8%
Other 47 18%
Unknown 47 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 41. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2021.
All research outputs
#683,061
of 19,211,930 outputs
Outputs from Revista Brasileira de Psiquiatria
#9
of 432 outputs
Outputs of similar age
#14,603
of 273,129 outputs
Outputs of similar age from Revista Brasileira de Psiquiatria
#1
of 2 outputs
Altmetric has tracked 19,211,930 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 432 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 273,129 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them