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Characterization of Epstein-Barr virus (EBV)-infected cells in EBV-associated hemophagocytic lymphohistiocytosis in two patients with X-linked lymphoproliferative syndrome type 1 and type 2

Overview of attention for article published in Herpesviridae, February 2012
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Mentioned by

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1 tweeter

Citations

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17 Dimensions

Readers on

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28 Mendeley
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Title
Characterization of Epstein-Barr virus (EBV)-infected cells in EBV-associated hemophagocytic lymphohistiocytosis in two patients with X-linked lymphoproliferative syndrome type 1 and type 2
Published in
Herpesviridae, February 2012
DOI 10.1186/2042-4280-3-1
Pubmed ID
Authors

Xi Yang, Xi Yang, Taizo Wada, Ken-Ichi Imadome, Naonori Nishida, Takeo Mukai, Mitsuhiro Fujiwara, Haruka Kawashima, Fumiyo Kato, Shigeyoshi Fujiwara, Akihiro Yachie, Xiaodong Zhao, Toshio Miyawaki, Hirokazu Kanegane

Abstract

X-linked lymphoproliferative syndrome (XLP) is a rare inherited immunodeficiency by an extreme vulnerability to Epstein-Barr virus (EBV) infection, frequently resulting in hemophagocytic lymphohistiocytosis (HLH). XLP are now divided into type 1 (XLP-1) and type 2 (XLP-2), which are caused by mutations of SH2D1A/SLAM-associated protein (SAP) and X-linked inhibitor of apoptosis protein (XIAP) genes, respectively. The diagnosis of XLP in individuals with EBV-associated HLH (EBV-HLH) is generally difficult because they show basically similar symptoms to sporadic EBV-HLH. Although EBV-infected cells in sporadic EBV-HLH are known to be mainly in CD8+ T cells, the cell-type of EBV-infected cells in EBV-HLH seen in XLP patients remains undetermined.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 2 7%
Argentina 1 4%
Unknown 25 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 21%
Student > Ph. D. Student 5 18%
Student > Master 5 18%
Professor > Associate Professor 4 14%
Other 3 11%
Other 3 11%
Unknown 2 7%
Readers by discipline Count As %
Medicine and Dentistry 12 43%
Agricultural and Biological Sciences 5 18%
Immunology and Microbiology 5 18%
Environmental Science 1 4%
Social Sciences 1 4%
Other 1 4%
Unknown 3 11%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 February 2012.
All research outputs
#6,217,039
of 10,488,535 outputs
Outputs from Herpesviridae
#9
of 15 outputs
Outputs of similar age
#52,444
of 101,598 outputs
Outputs of similar age from Herpesviridae
#1
of 3 outputs
Altmetric has tracked 10,488,535 research outputs across all sources so far. This one is in the 24th percentile – i.e., 24% of other outputs scored the same or lower than it.
So far Altmetric has tracked 15 research outputs from this source. They receive a mean Attention Score of 3.5. This one scored the same or higher as 6 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 101,598 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them