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Preventive effect of toothpastes with MMP inhibitors on human dentine erosion and abrasion in vitro

Overview of attention for article published in Journal of Applied Oral Science, February 2016
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Title
Preventive effect of toothpastes with MMP inhibitors on human dentine erosion and abrasion in vitro
Published in
Journal of Applied Oral Science, February 2016
DOI 10.1590/1678-775720150289
Pubmed ID
Authors

Angelica Reis Hannas, Melissa Thiemi Kato, Cristiane de Almeida Baldini Cardoso, Ana Carolina Magalhães, José Carlos Pereira, Leo Tjäderhane, Marília Afonso Rabelo Buzalaf

Abstract

The use of gels and mouthrinses with MMP inhibitors (chlorhexidine, and green tea extract) was shown to prevent erosive wear. The aim of this study was to analyze the protective effect of toothpastes containing MMP inhibitors on dentine loss induced by erosion in vitro. Material and Methods Five groups each containing 12 specimens of human root dentine were prepared. The specimens were subjected to 1 min erosion by immersion in a cola drink, 4 times a day, for 5 d. Each day, after the first and last erosive challenges, the specimens were brushed for 15 s with a slurry of dentifrice and water (1:3) containing placebo, 1,100 ppm fluoride, 0.61% green tea extract, 0.12% chlorhexidine or 0.004% chlorhexidine (commercial toothpaste). Between the acid challenges, the specimens were stored in artificial saliva with remineralizing potential until the next treatment. Dentine loss was determined using profilometry. Data were analyzed using one-way ANOVA after log transform (p<0.05). Results The mean wear values (μm) were as follows: placebo 1.83±0.53; 0.61% green tea extract 1.00±0.21; fluoride 1.27±0.43; 0.12% chlorhexidine 1.19±0.30; and 0.004% chlorhexidine 1.22±0.46. There was a significant difference in wear between placebo and all the treatment toothpastes, which did not differ from each other. Conclusion The results suggest that toothpastes containing MMP inhibitors are as effective as those based on NaF in preventing dentine erosion and abrasion.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 12%
Student > Ph. D. Student 6 12%
Student > Master 6 12%
Student > Postgraduate 4 8%
Lecturer > Senior Lecturer 2 4%
Other 10 20%
Unknown 17 33%
Readers by discipline Count As %
Medicine and Dentistry 22 43%
Biochemistry, Genetics and Molecular Biology 2 4%
Social Sciences 2 4%
Immunology and Microbiology 1 2%
Materials Science 1 2%
Other 0 0%
Unknown 23 45%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 January 2017.
All research outputs
#11,948,356
of 13,475,838 outputs
Outputs from Journal of Applied Oral Science
#158
of 194 outputs
Outputs of similar age
#224,060
of 267,127 outputs
Outputs of similar age from Journal of Applied Oral Science
#2
of 3 outputs
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So far Altmetric has tracked 194 research outputs from this source. They receive a mean Attention Score of 2.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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