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Food IgG4 antibodies are elevated not only in children with wheat allergy but also in children with gastrointestinal diseases

Overview of attention for article published in BMC Gastroenterology, March 2016
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (62nd percentile)

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5 tweeters
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2 Facebook pages

Citations

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18 Mendeley
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Title
Food IgG4 antibodies are elevated not only in children with wheat allergy but also in children with gastrointestinal diseases
Published in
BMC Gastroenterology, March 2016
DOI 10.1186/s12876-016-0450-3
Pubmed ID
Authors

Grażyna Czaja-Bulsa, Michał Bulsa, Aneta Gębala

Abstract

Food sIgG and sIgG4 are highly individually versatile. We put a hypothesis that one of the responsible factors is the presence of gastrointestinal inflammatory diseases. The objectives were: 1. An analysis of wheat and rice sIgG and sIgG4 in healthy children, children with IgE-mediated wheat allergy (WA), coeliac disease (CD) and Helicobacter pylori infection (HP). 2. Usability of wheat sIgG and sIgG4 in the WA diagnostics. We compared 388 each wheat and rice sIgG and sIgG4 in a group of 200 children: 50 WA (diagnosis, diet treatment, tolerance), 50 CD (diagnosis and remission), 50 HP and 50 healthy. SIgE, sIgG, sIgG4 were determined with the FEIA method (Pharmacia CAP System). In healthy children food sIgG were the lowest; no sIgG4 were found. In the CD diagnosis group wheat and rice sIgG and rice sIgG4 were the most common and their concentrations were the highest (p < .001, p < .05). Wheat sIgG4 were the highest in WA children (diagnosis and tolerance) to fall during the elimination diet (p < .05). Wheat and rice sIgG remained the same in all allergy phases. Rice sIgG also did not differ in the class G4. 1. Serum concentrations of wheat and rice sIgG and sIgG4 are elevated in children with CD, HP and WA. 2. Sub-clinical incidence of some gastrointestinal inflammatory diseases may be responsible for high individual versatility of food sIgG and sIgG4 concentrations in serum. 3. Wheat sIgG and sIgG4 in children do not correlate with WA clinical picture.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 18 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 33%
Student > Master 4 22%
Unspecified 3 17%
Student > Doctoral Student 2 11%
Student > Ph. D. Student 1 6%
Other 2 11%
Readers by discipline Count As %
Medicine and Dentistry 6 33%
Immunology and Microbiology 4 22%
Unspecified 3 17%
Nursing and Health Professions 2 11%
Biochemistry, Genetics and Molecular Biology 2 11%
Other 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 August 2019.
All research outputs
#7,019,690
of 13,865,625 outputs
Outputs from BMC Gastroenterology
#266
of 898 outputs
Outputs of similar age
#97,225
of 264,865 outputs
Outputs of similar age from BMC Gastroenterology
#1
of 1 outputs
Altmetric has tracked 13,865,625 research outputs across all sources so far. This one is in the 49th percentile – i.e., 49% of other outputs scored the same or lower than it.
So far Altmetric has tracked 898 research outputs from this source. They receive a mean Attention Score of 4.7. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 264,865 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 62% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them