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Potential Utility of the SYNTAX Score 2 in Patients Undergoing Left Main Angioplasty

Overview of attention for article published in Arquivos Brasileiros de Cardiologia, January 2016
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Title
Potential Utility of the SYNTAX Score 2 in Patients Undergoing Left Main Angioplasty
Published in
Arquivos Brasileiros de Cardiologia, January 2016
DOI 10.5935/abc.20160038
Pubmed ID
Authors

Sérgio Madeira, Luís Raposo, João Brito, Ricardo Rodrigues, Pedro Gonçalves, Rui Teles, Henrique Gabriel, Francisco Machado, Manuel Almeida, Miguel Mendes

Abstract

The revascularization strategy of the left main disease is determinant for clinical outcomes. We sought to 1) validate and compare the performance of the SYNTAX Score 1 and 2 for predicting major cardiovascular events at 4 years in patients who underwent unprotected left main angioplasty and 2) evaluate the long-term outcome according to the SYNTAX score 2-recommended revascularization strategy. We retrospectively studied 132 patients from a single-centre registry who underwent unprotected left main angioplasty between March 1999 and December 2010. Discrimination and calibration of both models were assessed by ROC curve analysis, calibration curves and the Hosmer-Lemeshow test. Total event rate was 26.5% at 4 years.The AUC for the SYNTAX Score 1 and SYNTAX Score 2 for percutaneous coronary intervention, was 0.61 (95% CI: 0.49-0.73) and 0.67 (95% CI: 0.57-0.78), respectively. Despite a good overall adjustment for both models, the SYNTAX Score 2 tended to underpredict risk. In the 47 patients (36%) who should have undergone surgery according to the SYNTAX Score 2, event rate was numerically higher (30% vs. 25%; p=0.54), and for those with a higher difference between the two SYNTAX Score 2 scores (Percutaneous coronary intervention vs. Coronary artery by-pass graft risk estimation greater than 5.7%), event rate was almost double (40% vs. 22%; p=0.2). The SYNTAX Score 2 may allow a better and individualized risk stratification of patients who need revascularization of an unprotected left main coronary artery. Prospective studies are needed for further validation.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Other 4 21%
Professor > Associate Professor 3 16%
Researcher 3 16%
Student > Ph. D. Student 2 11%
Professor 1 5%
Other 2 11%
Unknown 4 21%
Readers by discipline Count As %
Medicine and Dentistry 13 68%
Immunology and Microbiology 1 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Unknown 4 21%

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2016.
All research outputs
#7,875,283
of 13,643,660 outputs
Outputs from Arquivos Brasileiros de Cardiologia
#133
of 513 outputs
Outputs of similar age
#123,348
of 263,209 outputs
Outputs of similar age from Arquivos Brasileiros de Cardiologia
#1
of 1 outputs
Altmetric has tracked 13,643,660 research outputs across all sources so far. This one is in the 40th percentile – i.e., 40% of other outputs scored the same or lower than it.
So far Altmetric has tracked 513 research outputs from this source. They receive a mean Attention Score of 2.0. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,209 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them