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ANTIFUNGAL POTENTIAL OF PLANT SPECIES FROM BRAZILIAN CAATINGA AGAINST DERMATOPHYTES

Overview of attention for article published in Revista do Instituto de Medicina Tropical de Sao Paulo, March 2016
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Title
ANTIFUNGAL POTENTIAL OF PLANT SPECIES FROM BRAZILIAN CAATINGA AGAINST DERMATOPHYTES
Published in
Revista do Instituto de Medicina Tropical de Sao Paulo, March 2016
DOI 10.1590/s1678-9946201658018
Pubmed ID
Authors

Renata Perugini Biasi-Garbin, Fernanda de Oliveira Demitto, Renata Claro Ribeiro do Amaral, Magda Rhayanny Assunção Ferreira, Luiz Alberto Lira Soares, Terezinha Inez Estivalet Svidzinski, Lilian Cristiane Baeza, Sueli Fumie Yamada-Ogatta

Abstract

Trichophyton rubrum and Trichophyton mentagrophytes complex, or Trichophyton spp. are the main etiologic agents of dermatophytosis, whose treatment is limited by the high cost of antifungal treatments, their various side effects, and the emergence of resistance amongst these species. This study evaluated the in vitro antidermatophytic activity of 23 crude extracts from nine plant species of semiarid vegetation (caatinga) found in Brazil. The extracts were tested at concentrations ranging from 1.95 to 1,000.0 mg/mL by broth microdilution assay against the reference strains T. rubrum ATCC 28189 and T. mentagrophytesATCC 11481, and 33 clinical isolates of dermatophytes. All plants showed a fungicidal effect against both fungal species, with MIC/MFC values of the active extracts ranging from 15.6 to 250.0 µg/mL. Selected extracts of Eugenia uniflora (AcE), Libidibia ferrea (AE), and Persea americana (AcE) also exhibited a fungicidal effect against all clinical isolates of T. rubrum and T. mentagrophytes complex. This is the first report of the antifungal activity of Schinus terebinthifolius, Piptadenia colubrina, Parapiptadenia rigida, Mimosa ophthalmocentra, and Persea americana against both dermatophyte species.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 121 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 18 15%
Student > Master 14 12%
Student > Doctoral Student 12 10%
Student > Ph. D. Student 10 8%
Professor 8 7%
Other 22 18%
Unknown 37 31%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 18 15%
Agricultural and Biological Sciences 13 11%
Medicine and Dentistry 11 9%
Immunology and Microbiology 9 7%
Biochemistry, Genetics and Molecular Biology 8 7%
Other 20 17%
Unknown 42 35%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 June 2017.
All research outputs
#17,351,840
of 25,461,852 outputs
Outputs from Revista do Instituto de Medicina Tropical de Sao Paulo
#434
of 786 outputs
Outputs of similar age
#192,991
of 314,584 outputs
Outputs of similar age from Revista do Instituto de Medicina Tropical de Sao Paulo
#6
of 17 outputs
Altmetric has tracked 25,461,852 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 786 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,584 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 17 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.