Title |
Validation of the Functional Assessment of Chronic Illness Therapy Fatigue Scale relative to other instrumentation in patients with rheumatoid arthritis.
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Published in |
Journal of Rheumatology, May 2005
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Pubmed ID | |
Authors |
David Cella, Susan Yount, Mark Sorensen, Elliot Chartash, Nishan Sengupta, James Grober |
Abstract |
This study validated a brief measure of fatigue in rheumatoid arthritis (RA), the Functional Assessment of Chronic Illness Therapy (FACIT) Fatigue Scale. The FACIT Fatigue was tested along with measures previously validated in RA: the Multidimensional Assessment of Fatigue (MAF) and Medical Outcomes Study Short-Form 36 (SF-36) Vitality. The sample included 636 patients with RA enrolled in a 24 week double blind, randomized clinical trial (RCT) of adalimumab versus placebo. The FACIT Fatigue showed good internal consistency (alpha = 0.86 to 0.87), strong association with SF-36 Vitality (r = 0.73 to 0.84) and MAF (r = -0.84 to -0.88), and the ability to differentiate patients according to clinical change using the American College of Rheumatology (ACR) response criteria (ACR 20/50/70). Psychometric performance of the FACIT Fatigue scale was comparable to that of the other 2 fatigue measures. A minimally important difference in FACIT Fatigue change score of 3-4 points was confirmed in a separate sample of 271 patients with RA enrolled in a second double blind RCT of adalimumab versus placebo. The FACIT Fatigue is a brief, valid measure for monitoring this important symptom and its effects on patients with RA. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Netherlands | 1 | <1% |
Singapore | 1 | <1% |
Switzerland | 1 | <1% |
Unknown | 171 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 27 | 15% |
Researcher | 24 | 14% |
Student > Master | 23 | 13% |
Student > Bachelor | 15 | 9% |
Other | 14 | 8% |
Other | 32 | 18% |
Unknown | 40 | 23% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 62 | 35% |
Nursing and Health Professions | 16 | 9% |
Psychology | 15 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 11 | 6% |
Agricultural and Biological Sciences | 6 | 3% |
Other | 21 | 12% |
Unknown | 44 | 25% |