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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Conformational photoswitching of a synthetic peptide foldamer bound within a phospholipid bilayer
|
|---|---|
| Published in |
Science, March 2016
|
| DOI | 10.1126/science.aad8352 |
| Pubmed ID | |
| Authors |
Matteo De Poli, Wojciech Zawodny, Ophélie Quinonero, Mark Lorch, Simon J Webb, Jonathan Clayden |
| Abstract |
The dynamic properties of foldamers, synthetic molecules that mimic folded biomolecules, have mainly been explored in free solution. Here we report on the design, synthesis, and conformational behavior of photoresponsive foldamers bound in a phospholipid bilayer akin to a biological membrane phase. These molecules contain a chromophore, which can be switched between two configurations by different wavelengths of light, attached to a helical oligoamide that both promotes membrane insertion and communicates conformational change along its length. Light-induced structural changes in the chromophore are translated into global conformational changes, detected by monitoring the solid state(19)F nuclear magnetic resonance signals of a remote fluorine-containing residue located 1 to 2 nm away. The behavior of the foldamers in the membrane phase is similar to that of analogous compounds in organic solvents. |
X Demographics
The data shown below were collected from the profiles of 22 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 6 | 27% |
| United States | 2 | 9% |
| Spain | 2 | 9% |
| Japan | 1 | 5% |
| Unknown | 11 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 11 | 50% |
| Science communicators (journalists, bloggers, editors) | 5 | 23% |
| Scientists | 5 | 23% |
| Practitioners (doctors, other healthcare professionals) | 1 | 5% |
Mendeley readers
The data shown below were compiled from readership statistics for 173 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Netherlands | 1 | <1% |
| United States | 1 | <1% |
| Czechia | 1 | <1% |
| Unknown | 169 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 52 | 30% |
| Researcher | 31 | 18% |
| Student > Master | 22 | 13% |
| Student > Bachelor | 15 | 9% |
| Student > Doctoral Student | 8 | 5% |
| Other | 22 | 13% |
| Unknown | 23 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 98 | 57% |
| Biochemistry, Genetics and Molecular Biology | 11 | 6% |
| Earth and Planetary Sciences | 9 | 5% |
| Agricultural and Biological Sciences | 7 | 4% |
| Medicine and Dentistry | 4 | 2% |
| Other | 17 | 10% |
| Unknown | 27 | 16% |
Attention Score in Context
This research output has an Altmetric Attention Score of 119. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2020.
All research outputs
#357,810
of 25,791,949 outputs
Outputs from Science
#9,308
of 83,344 outputs
Outputs of similar age
#6,365
of 316,332 outputs
Outputs of similar age from Science
#171
of 1,158 outputs
Altmetric has tracked 25,791,949 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 83,344 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 66.0. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,332 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 1,158 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.