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Mouse-adapted scrapie strains 139A and ME7 overcome species barrier to induce experimental scrapie in hamsters and changed their pathogenic features

Overview of attention for article published in Virology Journal, March 2012
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Title
Mouse-adapted scrapie strains 139A and ME7 overcome species barrier to induce experimental scrapie in hamsters and changed their pathogenic features
Published in
Virology Journal, March 2012
DOI 10.1186/1743-422x-9-63
Pubmed ID
Authors

Qi Shi, Bao-Yun Zhang, Chen Gao, Jin Zhang, Hui-Ying Jiang, Cao Chen, Jun Han, Xiao-Ping Dong

Abstract

Transmissible spongiform encephalopathy (TSE) diseases are known to be zoonotic diseases that can infect different kinds of animals. The transmissibility of TSE, like that of other infectious diseases, shows marked species barrier, either being unable to infect heterologous species or difficult to form transmission experimentally. The similarity of the amino acid sequences of PrP among species is believed to be one of the elements in controlling the transmission TSE interspecies. Other factors, such as prion strains and host's microenvironment, may also participate in the process.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 30%
Student > Ph. D. Student 5 25%
Student > Bachelor 2 10%
Professor 1 5%
Other 1 5%
Other 1 5%
Unknown 4 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 25%
Biochemistry, Genetics and Molecular Biology 4 20%
Medicine and Dentistry 2 10%
Neuroscience 2 10%
Immunology and Microbiology 1 5%
Other 2 10%
Unknown 4 20%